Improvements to services at the European Nucleotide Archive.

Improvements to services at the European Nucleotide Archive.
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DOI:
10.1093/nar/gkp998
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发表时间:
2010-01
影响因子:
14.9
通讯作者:
Cochrane G
Cochrane G
中科院分区:
生物学2区
文献类型:
--
作者:
Leinonen R;Akhtar R;Birney E;Bonfield J;Bower L;Corbett M;Cheng Y;Demiralp F;Faruque N;Goodgame N;Gibson R;Hoad G;Hunter C;Jang M;Leonard S;Lin Q;Lopez R;Maguire M;McWilliam H;Plaister S;Radhakrishnan R;Sobhany S;Slater G;Ten Hoopen P;Valentin F;Vaughan R;Zalunin V;Zerbino D;Cochrane G

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欧洲核苷酸档案库(ENA;http://www.ebi.ac.uk/ena)是欧洲主要的核苷酸序列存档资源,保障开放的核苷酸数据获取,参与全球协作数据交换,并与科学出版流程相结合。作为将传统协作扩展到涵盖毛细管测序和新一代测序信息的积极倡导者,ENA在协作核苷酸存档领域做出了重大贡献。我们继续与合作者共同开发用于数据交换和公共数据传播的数据及元数据表示格式。除了DDBJ/EMBL/GenBank特征表格式外,我们还共享毛细管测序和新一代测序图谱的元数据格式,并使用且为美国国立生物技术信息中心(NCBI)的序列读取档案(SRA)工具包做出贡献,以实现新一代测序图谱的长期存储。在2009年期间,ENA显著改进了欧洲生物信息学研究所(EMBL - EBI)提供的序列提交、搜索和获取功能。在本文中,我们简要描述了我们档案库的内容和范围,并介绍了我们服务的主要改进。
The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is Europe’s primary nucleotide sequence archival resource, safeguarding open nucleotide data access, engaging in worldwide collaborative data exchange and integrating with the scientific publication process. ENA has made significant contributions to the collaborative nucleotide archival arena as an active proponent of extending the traditional collaboration to cover capillary and next-generation sequencing information. We have continued to co-develop data and metadata representation formats with our collaborators for both data exchange and public data dissemination. In addition to the DDBJ/EMBL/GenBank feature table format, we share metadata formats for capillary and next-generation sequencing traces and are using and contributing to the NCBI SRA Toolkit for the long-term storage of the next-generation sequence traces. During the course of 2009, ENA has significantly improved sequence submission, search and access functionalities provided at EMBL–EBI. In this article, we briefly describe the content and scope of our archive and introduce major improvements to our services.
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