Parma consensus statement on metabolic disruptors.
Parma consensus statement on metabolic disruptors.
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DOI：
10.1186/s12940-015-0042-7
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发表时间：
2015-06-20
期刊：
影响因子：
--
通讯作者：
Palanza P
中科院分区：
文献类型：
--
作者：
Heindel JJ;Vom Saal FS;Blumberg B;Bovolin P;Calamandrei G;Ceresini G;Cohn BA;Fabbri E;Gioiosa L;Kassotis C;Legler J;La Merrill M;Rizzir L;Machtinger R;Mantovani A;Mendez MA;Montanini L;Molteni L;Nagel SC;Parmigiani S;Panzica G;Paterlini S;Pomatto V;Ruzzin J;Sartor G;Schug TT;Street ME;Suvorov A;Volpi R;Zoeller RT;Palanza P
2014年5月16日至18日，一个多学科专家小组聚集在意大利帕尔马，参加由帕尔马大学主办的研讨会，讨论环境代谢干扰物、肥胖和相关代谢紊乱之间的潜在关系。讲习班的目标是：1。审查与被称为“代谢干扰物”的环境化学品在肥胖和代谢综合症中的作用有关的发现，特别注意动物模型和流行病学研究的最新发现；2. 确定可从现有动物和人类数据中可靠地得出的结论；3. 根据现有数据进行预测；和4。确定关键的知识差距和不确定的领域。共识声明的目的是帮助扩大对代谢干扰物在肥胖和代谢性疾病流行病中的作用的理解，通过评估目前的科学状况推动这一领域的发展，并确定关于环境化学品暴露在这些疾病中的作用的研究需求。我们建议将肥胖原的定义扩大到代谢干扰物的定义，以涵盖在肥胖、糖尿病和相关代谢疾病（包括代谢综合征）易感性改变中发挥作用的化学物质。
A multidisciplinary group of experts gathered in Parma Italy for a workshop hosted by the University of Parma, May 16–18, 2014 to address concerns about the potential relationship between environmental metabolic disrupting chemicals, obesity and related metabolic disorders. The objectives of the workshop were to: 1. Review findings related to the role of environmental chemicals, referred to as “metabolic disruptors”, in obesity and metabolic syndrome with special attention to recent discoveries from animal model and epidemiology studies; 2. Identify conclusions that could be drawn with confidence from existing animal and human data; 3. Develop predictions based on current data; and 4. Identify critical knowledge gaps and areas of uncertainty. The consensus statements are intended to aid in expanding understanding of the role of metabolic disruptors in the obesity and metabolic disease epidemics, to move the field forward by assessing the current state of the science and to identify research needs on the role of environmental chemical exposures in these diseases. We propose broadening the definition of obesogens to that of metabolic disruptors, to encompass chemicals that play a role in altered susceptibility to obesity, diabetes and related metabolic disorders including metabolic syndrome.
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影响因子：
10.4
作者：
La Merrill M;Cirillo PM;Terry MB;Krigbaum NY;Flom JD;Cohn BA
通讯作者：
Cohn BA
DOI：
10.1016/j.reprotox.2013.07.017
发表时间：
2013-12
期刊：
Reproductive toxicology (Elmsford, N.Y.)
影响因子：
--
作者：
Angle BM;Do RP;Ponzi D;Stahlhut RW;Drury BE;Nagel SC;Welshons WV;Besch-Williford CL;Palanza P;Parmigiani S;vom Saal FS;Taylor JA
通讯作者：
Taylor JA
影响因子：
15.1
作者：
Bolton, Jessica L.;Auten, Richard L.;Bilbo, Staci D.
通讯作者：
Bilbo, Staci D.
影响因子：
--
作者：
Burke, JP;Williams, K;Stern, MP
通讯作者：
Stern, MP
影响因子：
--
作者：
La Merrill, Michele;Birnbaum, Linda S.
通讯作者：
Birnbaum, Linda S.