REST: a toolkit for resting-state functional magnetic resonance imaging data processing.-猫眼课题宝

DOI：

10.1371/journal.pone.0025031

发表时间：

2011

期刊：

PloS one

影响因子：

3.7

通讯作者：

中科院分区：

综合性期刊3区

文献类型：

作者：

Song XW;Dong ZY;Long XY;Li SF;Zuo XN;Zhu CZ;He Y;Yan CG;Zang YF

来源链接：

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176805/?report=classic

近年来，静止状态fMRI（RS-FMRI）一直在引起越来越多的关注。但是，仍缺乏用于RS-FMRI数据处理的公开集成，易于使用的工具。我们开发了一个用于分析RS-FMRI数据的工具包，即静止状态fMRI数据分析工具包（REST）。 REST是在MATLAB中使用图形用户界面（GUI）开发的。在与SPM或AFNI进行数据预处理后，可以在REST中进行一些分析方法，包括基于线性相关性，区域同质性，低频波动（ALFF）和分数ALFF的功能连通性分析。在休息中实施了一些其他功能，包括DICOM分类器，线性趋势去除，带通滤波，时间课程提取，协变量的回归，图像计算器，统计分析和SLICE查看器（为结果可视化，多重比较校正等）。 REST是一个开源软件包，可以在http://www.restfmri.net上免费获得。

Resting-state fMRI (RS-fMRI) has been drawing more and more attention in recent years. However, a publicly available, systematically integrated and easy-to-use tool for RS-fMRI data processing is still lacking. We developed a toolkit for the analysis of RS-fMRI data, namely the RESting-state fMRI data analysis Toolkit (REST). REST was developed in MATLAB with graphical user interface (GUI). After data preprocessing with SPM or AFNI, a few analytic methods can be performed in REST, including functional connectivity analysis based on linear correlation, regional homogeneity, amplitude of low frequency fluctuation (ALFF), and fractional ALFF. A few additional functions were implemented in REST, including a DICOM sorter, linear trend removal, bandpass filtering, time course extraction, regression of covariates, image calculator, statistical analysis, and slice viewer (for result visualization, multiple comparison correction, etc.). REST is an open-source package and is freely available at http://www.restfmri.net.