What sleeping babies hear: a functional MRI study of interparental conflict and infants' emotion processing.
What sleeping babies hear: a functional MRI study of interparental conflict and infants' emotion processing.
复制标题
DOI：
10.1177/0956797612458803
复制
发表时间：
2013-05
影响因子：
8.2
通讯作者：
Pfeifer JH
中科院分区：
文献类型：
--
作者：
Graham AM;Fisher PA;Pfeifer JH
早年经历的逆境改变了大脑的发育。然而，记录这种关系的证据往往集中在严重的压力源上，并依赖于婴儿时期神经生物学功能的外围测量。本研究利用自然睡眠中的功能磁共振成像(FMRI)来研究较温和的环境应激源(非生理父母间冲突)与6-12个月大婴儿对声音情绪基调的神经处理之间的关系。主要的问题是，婴儿经历的父母间冲突是否与对声音的情绪基调，特别是非常愤怒的言语的神经反应有关。结果表明，母亲报告的更高的父母间冲突与婴儿对非常愤怒的言语与中性语言的神经反应增强有关，这些神经反应涉及情绪和压力反应和调节的几个大脑区域(包括嘴前扣带回皮质、尾状核、丘脑和下丘脑)-这表明即使是适度的环境压力也可能与婴儿时期的大脑功能有关。
Experiences of adversity in the early years of life alter the developing brain. However, evidence documenting this relationship often focuses on severe stressors and relies on peripheral measures of neurobiological functioning during infancy. The present study employed functional magnetic resonance imaging (fMRI) during natural sleep to examine associations between a more moderate environmental stressor (non-physical interparental conflict), and 6–12 month-old infants’ neural processing of emotional tone of voice. The primary question was whether interparental conflict experienced by infants is associated with neural responses to emotional tone of voice, particularly very angry speech. Results indicated that maternal report of higher interparental conflict was associated with infants’ heightened neural responses to very angry versus neutral speech across several brain regions implicated in emotion and stress reactivity and regulation (including rostral anterior cingulate cortex, caudate, thalamus and hypothalamus) – suggesting that even moderate environmental stress may be associated with brain functioning during infancy.
登录
查看更多内容
DOI：
10.1111/j.1540-5834.2009.00501.x
发表时间：
2009
影响因子：
9.5
作者：
El-Sheikh M;Kouros CD;Erath S;Cummings EM;Keller P;Staton L
通讯作者：
Staton L
影响因子：
3.7
作者：
Lopez-Duran, Nestor L.;Kovacs, Maria;George, Charles J.
通讯作者：
George, Charles J.
影响因子：
8.2
作者：
Loman MM;Gunnar MR;Early Experience, Stress, and Neurobehavioral Development Center
通讯作者：
Early Experience, Stress, and Neurobehavioral Development Center
影响因子：
2.1
作者：
Crockenberg, Susan C.;Leerkes, Esther M.;Lekka, Shamila K.
通讯作者：
Lekka, Shamila K.
影响因子：
3.6
作者：
PORTER, B;OLEARY, KD
通讯作者：
OLEARY, KD