The relationship between symptoms of depression and body weight in younger adults.
The relationship between symptoms of depression and body weight in younger adults.
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DOI：
10.1038/oby.2011.311
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发表时间：
2012-09
期刊：
影响因子：
6.9
通讯作者：
Wee, Christina C.
中科院分区：
文献类型：
--
作者：
Fowler-Brown, Angela G.;Ngo, Long H.;Wee, Christina C.
肥胖和抑郁之间可能存在双向关系，尽管之前的结果是相互矛盾的。我们研究的目的是确定年轻人的肥胖和抑郁症状之间是否存在双向关系，以及这种关系是否随社会人口因素而变化。我们使用 1979 年全国青年纵向调查中 7,980 名参与者的数据来检验 1992 年的基线抑郁症状（CES-D 的七项分量表得分≥10）是否可以预测 1992 年至 1994 年间 BMI 的调整百分比变化。然后，在调整混杂因素后，我们检验了 1992 年的肥胖是否可以预测 1994 年抑郁症状的发展。我们发现，除西班牙裔女性外，基线抑郁症状的存在与 BMI 百分比的增加并不存在前瞻性关联。此外，总体样本中基线肥胖与未来抑郁症状的较高风险无关（调整后风险比 (RR) 1.20；99% CI 0.91–1.60）。然而，在社会经济地位较高的人群中，与非肥胖者相比，肥胖与抑郁症状的风险几乎增加了一倍（最高收入类别：调整后的 RR 1.97；99% CI 1.14-3.40）。我们的结论是，尽管肥胖与总体人群中抑郁症状的风险无关，但肥胖与社会经济地位较高的人群出现抑郁症状的风险增加相关。社会人口因素可能是肥胖与抑郁之间关系的重要调节因素。
A bidirectional relationship between obesity and depression may exist, though previous results are conflicting. The objectives of our study were to determine whether there is a bidirectional relationship between obesity and symptoms of depression in younger adults and whether this relationship varies with sociodemographic factors. We used data from 7,980 participants in the National Longitudinal Survey of Youth 1979 to examine whether baseline depressive symptoms (score ≥ 10 on a seven-item subscale of the CES-D) in 1992, predicted adjusted percent change in BMI between 1992 and 1994. We then examined whether obesity in 1992 predicted the development of symptoms of depression in 1994, after adjustment for confounders. We found that the presence of baseline depressive symptoms was not prospectively associated with increase in percent BMI, except in Hispanic women. Additionally, baseline obesity was not associated with higher risk of future symptoms of depression in the sample overall (adjusted risk ratio (RR) 1.20; 99% CI 0.91–1.60). However, in those of higher socioeconomic status, obesity was associated with almost double the risk of depressive symptoms compared to nonobese (highest income category: adjusted RR 1.97; 99% CI 1.14–3.40). We concluded that although obesity was not associated with risk of depression symptoms in the population overall, obesity was associated with an increased risk of developing depressive symptoms in those of higher socioeconomic status. Sociodemographic factors may be important modifiers of the relationship between obesity and depression.
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