Greenness and allergies: evidence of differential associations in two areas in Germany.
Greenness and allergies: evidence of differential associations in two areas in Germany.
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DOI：
10.1136/jech-2014-203903
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发表时间：
2014-08
影响因子：
6.3
通讯作者：
Heinrich J
中科院分区：
文献类型：
--
作者：
Fuertes E;Markevych I;von Berg A;Bauer CP;Berdel D;Koletzko S;Sugiri D;Heinrich J
绿色对健康的积极影响越来越多地被报道，尽管关于过敏结果的研究仍然有限且相互矛盾。我们在德国北部和南部的两个出生队列(GINIplus和Lisaplus)中检验了居住环境的绿色化是否与儿时医生诊断为过敏性鼻炎、眼睛和鼻子症状以及空气过敏原敏感有关(NTotal=5803)。使用归一化差异植被指数(一种绿色生物质密度指标)定义了10年住宅地址周围500 m缓冲区内的平均住宅绿色度。每个研究区域(基尼/丽莎南部和基尼/丽莎北部)使用针对宿主和环境协变量调整的通用估计方程来评估纵向相关性。尽管相同的研究设计和统计模型，绿色效应在两个研究领域是不同的。在城市基尼/丽莎南部地区，过敏性鼻炎与眼睛和鼻子症状的相关性增加。相比之下，在基尼/丽莎北部的农村地区，对这些结果和空气过敏原敏感性的风险估计明显低于1。在缓冲区大小和地址(出生年和6 年)上，特定区域的关联相似，并且在空气污染和人口密度分层后仍然是不同的。对现有和未来关于绿化和绿地的单一区域研究应谨慎解读。
Positive greenness effects on health are increasingly reported, although studies on allergic outcomes remain limited and conflicting. We examined whether residential greenness is associated with childhood doctor diagnosed allergic rhinitis, eyes and nose symptoms and aeroallergen sensitisation using two combined birth cohorts (GINIplus and LISAplus) followed from birth to 10 years in northern and southern Germany (Ntotal=5803). Mean residential greenness in a 500 m buffer around the 10-year home addresses was defined using the Normalized Difference Vegetation Index, a green biomass density indicator. Longitudinal associations were assessed per study area (GINI/LISA South and GINI/LISA North) using generalised estimation equations adjusted for host and environmental covariates. Despite identical study designs and statistical modelling, greenness effects differed across the two study areas. Associations were elevated for allergic rhinitis and eyes and nose symptoms in the urban GINI/LISA South area. In contrast, risk estimates were significantly below one for these outcomes and aeroallergen sensitisation in rural GINI/LISA North. Area-specific associations were similar across buffer sizes and addresses (birth and 6 years) and remained heterogeneous after air pollution and population density stratification. Existing and future single-area studies on greenness and green spaces should be interpreted with caution.
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DOI：
10.1073/pnas.1205624109
发表时间：
2012-05-22
影响因子：
11.1
作者：
Hanski, Ilkka;von Hertzen, Leena;Haahtela, Tari
通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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影响因子：
12.4
作者：
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通讯作者：
Citterio, S.
影响因子：
4.8
作者：
Markevych, Iana;Fuertes, Elaine;Heinrich, Joachim
通讯作者：
Heinrich, Joachim