The role of dendritic cell precursors in tumour vasculogenesis.
The role of dendritic cell precursors in tumour vasculogenesis.
复制标题
树突状细胞前体在肿瘤血管生成中的作用。
DOI:
10.1038/sj.bjc.6602476
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发表时间:
2005-04-11
影响因子:
8.8
通讯作者:
Conejo-Garcia, JR
中科院分区:
文献类型:
--
作者:
Coukos, G;Benencia, F;Buckanovich, RJ;Conejo-Garcia, JR
In this review, we discuss the recent identification in vivo of a population of CD11c+ cells exhibiting simultaneous expression of both endothelial and dendritic cell markers, termed vascular leukocytes (VLCs). VLCs are highly represented in human ovarian carcinomas and, depending on the milieu, can assemble into functional blood vessels or act as antigen-presenting cells. The identification of dendritic cell precursors as bipotent cells has important implications for the physiopathology and therapy of tumours. VLCs emerge as a novel therapeutic target against tumour vascularisation.
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影响因子:
56.9
作者:
Asahara, T;Murohara, T;Isner, JM
通讯作者:
Isner, JM
影响因子:
20.3
作者:
Rivollier, A;Mazzorana, M;Servet-Delprat, C
通讯作者:
Servet-Delprat, C
影响因子:
20.3
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Conejo-Garcia, JR;Buckanovich, RJ;Coukos, G
通讯作者:
Coukos, G
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Havemann, K
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