Metaproteomic analysis of human gut microbiome in digestive and metabolic diseases.
Metaproteomic analysis of human gut microbiome in digestive and metabolic diseases.
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DOI:
10.1016/bs.acc.2019.12.002
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发表时间:
2020
影响因子:
--
通讯作者:
Chen, Ru
中科院分区:
文献类型:
--
作者:
Pan, Sheng;Chen, Ru
Metaproteomics, as a subfield of proteomics, has quickly emerged as a pivotal tool for global characterization of a microbiome system at a functional level. It has been increasingly applied in studying human digestive and metabolic diseases, and provides information-rich data to identify the dysbiosis of human gut microbiome related to healthy or disease states to elucidate the molecular events underlying host-microbiota interplays. While significant technical challenges still exist, this emerging technology has been demonstrated to provide essential information in interrogating functional changes in the human gut microbiome, complementary to metagenomics and metatranscriptomics. This chapter overviews the overall metaproteomic work flow and its recent applications in studying human gut microbiome relevant to digestive and metabolic diseases.
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影响因子:
6.4
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Maier TV;Lucio M;Lee LH;VerBerkmoes NC;Brislawn CJ;Bernhardt J;Lamendella R;McDermott JE;Bergeron N;Heinzmann SS;Morton JT;González A;Ackermann G;Knight R;Riedel K;Krauss RM;Schmitt-Kopplin P;Jansson JK
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Jansson JK
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3.7
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Erickson AR;Cantarel BL;Lamendella R;Darzi Y;Mongodin EF;Pan C;Shah M;Halfvarson J;Tysk C;Henrissat B;Raes J;Verberkmoes NC;Fraser CM;Hettich RL;Jansson JK
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Jansson JK
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4.4
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3.3
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Heyer, R.
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5.5
作者:
Petriz BA;Franco OL
通讯作者:
Franco OL