The costs and benefits of primary prevention of zoonotic pandemics.

The costs and benefits of primary prevention of zoonotic pandemics.
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DOI:
10.1126/sciadv.abl4183
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发表时间:
2022-02-04
期刊:
影响因子:
13.6
通讯作者:
Dobson AP
Dobson AP
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Bernstein AS;Ando AW;Loch-Temzelides T;Vale MM;Li BV;Li H;Busch J;Chapman CA;Kinnaird M;Nowak K;Castro MC;Zambrana-Torrelio C;Ahumada JA;Xiao L;Roehrdanz P;Kaufman L;Hannah L;Daszak P;Pimm SL;Dobson AP

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在过去的世纪里,病毒性人畜共患大流行病造成的生命损失和经济成本稳步上升。著名的政策制定者已经提出了一些计划,认为应对未来大流行灾难的最佳方式应该是“发现和遏制新出现的人畜共患病威胁”。换句话说,我们应该在人类生病后才采取行动。我们完全不同意。人类与野生动物有着广泛的接触,已知野生动物携带着大量的病毒,其中许多病毒尚未感染人类。我们计算了新出现的病毒性人畜共患疾病造成的年度损失。我们探讨了三个实际行动,以尽量减少未来流行病的影响:更好地监测病原体溢出和病毒基因组学和血清学的全球数据库的发展,更好地管理野生动物贸易,并大幅减少森林砍伐。我们发现,这些初级流行病预防行动的成本不到每年因新出现的病毒性人畜共患病而失去的生命价值的1/20,并且具有实质性的共同利益。初级大流行预防行动的成本不到每年因新出现的病毒性人畜共患病而丧失的生命价值的1/20。
The lives lost and economic costs of viral zoonotic pandemics have steadily increased over the past century. Prominent policymakers have promoted plans that argue the best ways to address future pandemic catastrophes should entail, “detecting and containing emerging zoonotic threats.” In other words, we should take actions only after humans get sick. We sharply disagree. Humans have extensive contact with wildlife known to harbor vast numbers of viruses, many of which have not yet spilled into humans. We compute the annualized damages from emerging viral zoonoses. We explore three practical actions to minimize the impact of future pandemics: better surveillance of pathogen spillover and development of global databases of virus genomics and serology, better management of wildlife trade, and substantial reduction of deforestation. We find that these primary pandemic prevention actions cost less than 1/20th the value of lives lost each year to emerging viral zoonoses and have substantial cobenefits. Primary pandemic prevention actions cost less than 1/20th the value of lives lost each year to emerging viral zoonoses.
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