Heart rate variability during sleep in detoxified alcohol-dependent males: A comparison with healthy controls.
Heart rate variability during sleep in detoxified alcohol-dependent males: A comparison with healthy controls.
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DOI：
10.4103/0019-5545.111458
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发表时间：
2013-04
影响因子：
3.1
通讯作者：
Gangadhar BN
中科院分区：
文献类型：
--
作者：
Ganesha S;Thirthalli J;Muralidharan K;Benegal V;Gangadhar BN
酒精依赖可导致自主神经病变，导致心脏病发病率和死亡率增加。这以前已经使用心率变异性进行了评估。在这项研究中，我们比较了酒精依赖患者与健康对照者的睡眠心率变异性。本研究在NIMHANS，班加罗尔进行。采用病例对照研究设计。对20例男性酒依赖住院患者在脱毒后第5天进行睡眠心率变异性的检测。睡眠心率变异性也记录在18个年龄和性别匹配的健康对照。连续变量采用t检验，离散变量采用卡方检验。与对照组相比，患者的时域和频域测量值均显著降低，表明酒精依赖个体的HRV降低。酒精依赖时HRV降低提示潜在的自主神经病变。
Alcohol dependence can lead to autonomic neuropathy resulting in increased cardiac morbidity and mortality. This has previously been evaluated using heart-rate variability. We compared sleep heart-rate variability of alcohol-dependent patients with that of healthy controls in this study. This study was conducted at NIMHANS, Bangalore. A case control study design was adopted. Sleep heart-rate variability of 20 male alcohol-dependent inpatients was recorded on the 5th day after detoxification. Sleep heart-rate variability was also recorded in 18 age- and gender-matched healthy controls. The groups were compared using t-test for continuous variables and Chi-squared test for discrete variables. Both time and frequency domain measures were significantly lower in the patients as compared to the controls, indicating decreased HRV in alcohol-dependent individuals. Decreased HRV in alcohol dependence indicates potential autonomic neuropathy.
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DOI：
10.1111/j.1530-0277.2012.01913.x
发表时间：
2013-01-01
影响因子：
3.2
作者：
Quintana, Daniel S.;McGregor, Iain S.;Kemp, Andrew H.
通讯作者：
Kemp, Andrew H.
影响因子：
10.6
作者：
Rajan, I;Murthy, PJNV;Janakiramaiah, N
通讯作者：
Janakiramaiah, N
影响因子：
3.3
作者：
Irwin, MR;Valladares, EM;Ehlers, CL
通讯作者：
Ehlers, CL
影响因子：
3.8
作者：
Jermendy, G
通讯作者：
Jermendy, G
影响因子：
5
作者：
Karimullah, K;George, DT;DePetrillo, PB
通讯作者：
DePetrillo, PB