Staphylococcus aureus infections in US veterans, Maryland, USA, 1999-2008.

Staphylococcus aureus infections in US veterans, Maryland, USA, 1999-2008.
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DOI:
10.3201/eid1703.100502
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发表时间:
2011-03
影响因子:
11.8
通讯作者:
Roghmann MC
Roghmann MC
中科院分区:
医学2区
文献类型:
--
作者:
Tracy LA;Furuno JP;Harris AD;Singer M;Langenberg P;Roghmann MC

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Trends in Staphylococcus aureus infections are not well described. To calculate incidence in overall S. aureus infection and invasive and noninvasive infections according to methicillin susceptibility and location, we conducted a 10-year population-based retrospective cohort study (1999–2008) using patient-level data in the Veterans Affairs Maryland Health Care System. We found 3,674 S. aureus infections: 2,816 (77%) were noninvasive; 2,256 (61%) were methicillin-resistant S. aureus (MRSA); 2,517 (69%) were community onset, and 1,157 (31%) were hospital onset. Sixty-one percent of noninvasive infections were skin and soft tissue infections; 1,112 (65%) of these were MRSA. Ten-year averaged incidence per 100,000 veterans was 749 (± 132 SD, range 549–954) overall, 178 (± 41 SD, range 114–259) invasive, and 571 (± 152 SD, range 364–801) noninvasive S. aureus infections. Incidence of all S. aureus infections significantly increased (p<0.001), driven by noninvasive, MRSA, and community-onset infections (p<0.001); incidence of invasive S. aureus infection significantly decreased (p<0.001).
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