Youth E-Cigarette Use and Functionally Important Respiratory Symptoms: The Population Assessment of Tobacco and Health (PATH) Study Waves 3 and 4.

Youth E-Cigarette Use and Functionally Important Respiratory Symptoms: The Population Assessment of Tobacco and Health (PATH) Study Waves 3 and 4.
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DOI:
10.3390/ijerph192215324
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发表时间:
2022-11-19
影响因子:
--
通讯作者:
Jiang, Nan
Jiang, Nan
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Stevens, Elizabeth R.;Xu, Shu;Niaura, Raymond;Cleland, Charles M.;Sherman, Scott E.;Mai, Andi;Karey, Emma;Jiang, Nan

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年轻人使用电子烟对呼吸系统的影响尚未完全了解。这项研究调查了美国青年使用电子烟与功能重要的呼吸道症状的有效指数之间的纵向关联。分析了烟草与健康研究人口评估第3-4波的数据。样本包括在基线(第3波)时没有哮喘的青少年(12-17岁),他们完成了随访调查(第4波),并且没有分析变量的缺失数据(n = 3899)。暴露是基线时的电子烟使用状态(从未,以前或当前)。结果是基于波4时7个喘息项目的反应的呼吸症状指数。指数≥2定义为具有功能重要的呼吸道症状。滞后logistic回归模型通过可燃烟草使用状态(从未或曾经)检查基线电子烟使用与随访时功能重要的呼吸道症状之间的关联,并控制基线协变量。在基线时,13.7%的参与者报告以前使用过电子烟,4.3%的参与者报告目前使用电子烟。无论可燃烟草使用状况如何,基线电子烟使用并没有增加随访时具有功能重要的呼吸道症状的几率。未来对更大规模的电子烟使用者进行更长时间的随访研究,将提高我们对年轻人使用电子烟相关呼吸风险的理解。
Respiratory effects of e-cigarette use among youth are not fully understood. This study investigated the longitudinal association between e-cigarette use and a validated index of functionally important respiratory symptoms among US youth. Data from Waves 3–4 of the Population Assessment of Tobacco and Health Study were analyzed. The sample included youth (aged 12–17) without asthma at baseline (Wave 3), who completed a follow-up survey (Wave 4), and were not missing data for analytic variables (n = 3899). Exposure was e-cigarette use status (never, former, or current) at baseline. The outcome was a respiratory symptom index based on responses for seven wheezing items at Wave 4. An index of ≥2 was defined as having functionally important respiratory symptoms. Lagged logistic regression models examined the association between baseline e-cigarette use and functionally important respiratory symptoms at follow-up by combustible tobacco use status (never or ever), and controlling for baseline covariates. At baseline, 13.7% of participants reported former e-cigarette use, and 4.3% reported current use. Baseline e-cigarette use did not increase the odds of having functionally important respiratory symptoms at follow-up regardless of combustible tobacco use status. Future research on larger populations of e-cigarette users with longer follow-up periods will improve our understanding of the respiratory risks associated with e-cigarette use among youth.
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发表时间: 2021-09-14
影响因子: --
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