Chloride cells and osmoregulation.
Chloride cells and osmoregulation.
复制标题
氯细胞和渗透压调节。
DOI:
10.1038/ki.1996.225
复制
发表时间:
1996
影响因子:
19.6
通讯作者:
Zadunaisky,JA
中科院分区:
文献类型:
--
作者:
Zadunaisky,JA
Chloride cells and osmoregulation.The chloride cells of the gill secretory epithelium of fish that make the transition from fresh water to sea water adapt to the increased salinity by responding to a rapid signal that stimulates chloride secretion. In this paper, data are presented supporting the view that the transient increase in plasma osmolarity that can be measured during the transition is responsible for the stimulation of chloride secretion. A maximal increase of 65 mOsm in the plasma ofFundulus heteroclitus(the killifish) was found during acclimation to sea water. Similar or greater increases of osmolarity induced by mannitol on the basolateral side of isolated opercular epithelial membranes of the same species of fish containing great numbers of chloride cells produced stimulation of chloride secretion detected as the short circuit current. The shrinkage of the chloride cell activates the Na-K-2Cl cotransporter, and the Na/H exchanger and requires the integrity of apical chloride channels and normal levels of Ca. A Cl/HCO3exchanger did not participate in this osmotic response to higher salinity. Chloride cell volume responses to osmolarity were studied with imagine and quantitative optics.
登录
查看更多内容
DOI:
10.1016/b978-0-12-775280-8.50019-6
发表时间:
1982
期刊:
Autonomic Neuroscience
影响因子:
--
作者:
K. Degnan;J. Zadunaisky
通讯作者:
J. Zadunaisky
DOI:
10.1113/jphysiol.1979.sp012942
发表时间:
1979
期刊:
The Journal of Physiology
影响因子:
--
作者:
K. Degnan;J. Zadunaisky
通讯作者:
J. Zadunaisky
影响因子:
5.5
作者:
Keys, A;Willmer, EN
通讯作者:
Willmer, EN
影响因子:
--
作者:
Smith, HW;Farinacci, N;Breitweiser, A
通讯作者:
Breitweiser, A
DOI:
10.1152/ajpregu.1988.254.1.r27
发表时间:
1988
期刊:
The American journal of physiology
影响因子:
--
作者:
Scheide,JI;Zadunaisky,JA
通讯作者:
Zadunaisky,JA