Oral Microbiome Geography: Micron-Scale Habitat and Niche.

Oral Microbiome Geography: Micron-Scale Habitat and Niche.
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DOI:
10.1016/j.chom.2020.07.009
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发表时间:
2020-08-12
影响因子:
30.3
通讯作者:
Borisy GG
Borisy GG
中科院分区:
医学1区
文献类型:
--
作者:
Mark Welch JL;Ramírez-Puebla ST;Borisy GG

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口腔在通过唾液相互交流时呈现出多种局部环境。口腔内微生物的空间组织是由动态平衡中的反作用力形成的——唾液流动和粘附、脱落和定植——以及微生物和宿主之间的相互作用。在这里,我们回顾了最近的证据,证实口腔微生物在口腔内的个体栖息地是专门的,微生物的栖息地和生态位是由微米尺度的梯度和短期和长期相互作用相结合来定义的。微米尺度结构阐明了单个分类群的作用,并提供了对其群落生态学和潜在致病性的见解。
The mouth presents a multiplicity of local environments in communication with one another via saliva. The spatial organization of microbes within the mouth is shaped by opposing forces in dynamic equilibrium—salivary flow and adhesion, shedding and colonization—and by interactions among and between microbes and the host. Here we review recent evidence confirming that oral microbes are specialized for individual habitats within the mouth and that microbial habitats and niches are defined by micron-scale gradients in combination with short- and long-range interactions. Micron-scale structure illuminates the roles of individual taxa and provides insight into their community ecology and potential pathogenicity.
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