Antioxidant activities of various extracts from Artemisisa selengensis Turcz (LuHao).
Antioxidant activities of various extracts from Artemisisa selengensis Turcz (LuHao).
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DOI：
10.3390/molecules15074934
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发表时间：
2010-07-16
期刊：
影响因子：
--
通讯作者：
Chen Y
中科院分区：
文献类型：
--
作者：
Shi F;Jia X;Zhao C;Chen Y
采用体外和体内抗氧化试验研究了藜蒿（AST）各提取物和部位的抗氧化活性。采用FRAP、DPPH和ABTS法对提取物进行体外抗氧化活性评价。评价了水提取物（WE）在降低雄性小鼠氧化应激中的作用。酚酸类化合物具有显著的抗氧化活性。从三个体外抗氧化试验的结果，WE被发现具有最高的抗氧化活性，和WE亚组分中，水溶性部分具有显着的抗氧化活性。体内抗氧化实验结果表明，高剂量的WE能显著降低正常饮食和D-（+）半乳糖组小鼠的MDA水平（p < 0.05），且高剂量组小鼠的SOD活性最高。这些体外和体内研究表明，提取物，特别是从AST的WE，具有显着的抗氧化和自由基清除活性。综上所述，我们认为AST有可能作为天然抗氧化剂的丰富来源。
The antioxidant activities of the various extracts and fractions from the herbs of Artemisia selegensis Turcz (AST) were investigated by in vitro and in vivo assays. FRAP, DPPH and ABTS assays were used to evaluate the antioxidant activities of the extracts/fractions in vitro. The effect of water extract (WE) in reducing oxidative stress in male mice was evaluated. Phenolic acid compounds contribute significantly to the antioxidant activity. From the results of three in vitro antioxidant assays, WE was found to have the highest antioxidant activity, and among the WE subfractions, the water soluble fraction has a significant antioxidant activity. The in vivo antioxidant assay results showed that high doses of WE significantly decrease the MDA level compared to normal diet and D-(+) galactose group (p < 0.05), and the SOD activity of mice given a high dose of WE was the highest. These in vitro and in vivo studies demonstrated that the extracts, especially the WE from AST, have significant antioxidant and free radical scavenging activities. In summary, we propose that AST could be potentially used as a rich source of natural antioxidants.
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DOI：
10.1111/j.1365-2710.2008.00993.x
发表时间：
2009-04-01
影响因子：
2
作者：
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通讯作者：
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影响因子：
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影响因子：
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作者：
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影响因子：
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作者：
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通讯作者：
Oomah, BD
DOI：
10.3390/molecules15042139
发表时间：
2010-03-25
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
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通讯作者：
Palanisamy UD