Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures.

Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures.
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DOI:
10.1186/s13229-021-00419-9
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发表时间:
2021-05-27
期刊:
影响因子:
6.2
通讯作者:
Hardan AY
Hardan AY
中科院分区:
医学1区
文献类型:
--
作者:
Uljarević M;Jo B;Frazier TW;Scahill L;Youngstrom EA;Hardan AY

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自闭症谱系障碍(ASD)的限制性重复行为(RRB)包括几个不同的领域。然而,常用的ASD测量提供了广泛的RRB评分,而不是评估单独的RRB领域。本次调查的主要目的是对社会反应性量表(SRS-2)、社交沟通问卷(SCQ)、自闭症诊断访谈修订版(ADI-R)和自闭症诊断观察表(ADOS)的能力进行心理测量评估,以捕捉不同的RRB结构。探索性结构方程模型使用了SRS-2、SCQ、ADI-R和ADOS的个体条目水平的数据。数据是从现有的五个公开数据库获得的。对于SRS-2,最终样本包括N = 16,761人(MAGE = 9.43,SD = 3.73;女性18.5%);SCQ,N = 15,840人(MAGE = 7.99,SD = 4.06;女性18.1%);ADI-R,N = 8985(MAGE = 8.86,SD = 4.68;女性19.4%);ADOS,N = 6314例(MAGE = 12.29,SD = 6.79;女性17.7%)。三因素结构对所有测量的数据提供了最优和可解释的拟合(比较拟合指数 ≥ .983,塔克-刘易斯指数 ≥ .966,逼近均方误差 ≤ .028)。重复运动行为、对一致性的坚持以及不寻常或受限的利益因素在所有工具中都出现了。没有为ADOS确定可接受的匹配。这里使用的五个数据集提供了RRB项目分数的大范围和广泛分布。然而,用于建立收敛和发散效度的措施仅适用于样本的一部分。报告的发现为使用常规ASD测量捕获重要的RRB域提供了希望,并强调了测量开发的必要性。网上版载有补充材料,可在10.1186/s13229-021-00419-9查阅。
Restricted and repetitive behaviors (RRB) in autism spectrum disorder (ASD) encompass several distinct domains. However, commonly used general ASD measures provide broad RRB scores rather than assessing separate RRB domains. The main objective of the current investigation was to conduct a psychometric evaluation of the ability of the Social Responsiveness Scale (SRS-2), the Social Communication Questionnaire (SCQ), the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS) to capture different RRB constructs. Exploratory Structural Equation Modeling (ESEM) was conducted using individual item-level data from the SRS-2, SCQ, ADI-R and the ADOS. Data were obtained from five existing publicly available databases. For the SRS-2, the final sample consisted of N = 16,761 individuals (Mage = 9.43, SD = 3.73; 18.5% female); for the SCQ, of N = 15,840 (Mage = 7.99, SD = 4.06; 18.1% female); for the ADI-R, of N = 8985 (Mage = 8.86, SD = 4.68; 19.4% female); and for the ADOS, of N = 6314 (Mage = 12.29, SD = 6.79; 17.7% female). The three-factor structure provided the most optimal and interpretable fit to data for all measures (comparative fit index ≥ .983, Tucker Lewis index ≥ .966, root mean square error of approximation ≤ .028). Repetitive-motor behaviors, insistence on sameness and unusual or circumscribed interests factors emerged across all instruments. No acceptable fit was identified for the ADOS. The five datasets used here afforded a large as well as wide distribution of the RRB item scores. However, measures used for establishing convergent and divergent validity were only available for a portion of the sample. Reported findings offer promise for capturing important RRB domains using general ASD measures and highlight the need for measurement development. The online version contains supplementary material available at 10.1186/s13229-021-00419-9.
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发表时间: 2018
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