Airborne bioaerosols and their impact on human health.

Airborne bioaerosols and their impact on human health.
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DOI:
10.1016/j.jes.2017.08.027
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发表时间:
2018-05
期刊:
Journal of environmental sciences (China)
影响因子:
--
通讯作者:
Jahan SA
Jahan SA
中科院分区:
其他
文献类型:
--
作者:
Kim KH;Kabir E;Jahan SA

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生物气溶胶由生物来源的气溶胶组成,如代谢物、毒素或环境中无处不在的微生物碎片。国际上对生物气溶胶的兴趣迅速增加,以扩大对其识别、量化、分布和健康影响(例如传染病和呼吸道疾病、过敏和癌症)的知识库。然而,基于传统培养方法的生物气溶胶风险评估受到以下几个因素的进一步阻碍:(1)待调查微生物或衍生物的复杂性;(二)抽样的目的、方法和地点;(3)缺乏有效的定量标准(例如,暴露标准和剂量效应关系)。虽然接触某些微生物被认为对健康有益,但需要进行更多的研究,以适当评估其潜在的健康危害,包括个体间易感性、与非生物制剂的相互作用以及许多已证实/未证实的健康影响(例如,特应性和特应性疾病)。
Bioaerosols consist of aerosols originated biologically such as metabolites, toxins, or fragments of microorganisms that are present ubiquitously in the environment. International interests in bioaerosols have increased rapidly to broaden the pool of knowledge on their identification, quantification, distribution, and health impacts (e.g., infectious and respiratory diseases, allergies, and cancer). However, risk assessment of bioaerosols based on conventional culture methods has been hampered further by several factors such as: (1) the complexity of microorganisms or derivatives to be investigated; (2) the purpose, techniques, and locations of sampling; and (3) the lack of valid quantitative criteria (e.g., exposure standards and dose/effect relationships). Although exposure to some microbes is considered to be beneficial for health, more research is needed to properly assess their potential health hazards including inter-individual susceptibility, interactions with non-biological agents, and many proven/unproven health effects (e.g., atopy and atopic diseases).
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