The protective effect of MD-resistant breeding and HVT vaccination against immunosuppression caused by MDV infection in chickens

The protective effect of MD-resistant breeding and HVT vaccination against immunosuppression caused by MDV infection in chickens
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抗MD选育及HVT疫苗接种对MDV感染鸡免疫抑制的保护作用

DOI:
10.1080/09540101003674342
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发表时间:
2010-08
影响因子:
3
通讯作者:
韦平
韦平
中科院分区:
农林科学3区
文献类型:
--
作者:
韦平

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通过对禽流感(AI)和新城疫(ND)疫苗的抗体滴定,评价了马立克氏病(MD)抗性育种和疫苗接种对马立克氏病强毒(MDV)免疫抑制的影响。结果表明,未攻毒组雏鸡对新城疫和禽流感病毒的血凝抑制效价显著高于攻毒组(P<0.05),耐药组显著高于普通禽组(P&t;0.05),火鸡疱疹病毒(HVT)免疫组显著高于未攻毒组(P<0.05)。结果表明,马立克氏病病毒感染能显著抑制新城疫和禽流感疫苗的免疫应答,抗马立克氏病育种和接种新城疫疫苗可显著提高对这一抑制的抵抗力。
Abstract By the titrations of the antibody response to the vaccinations of avian influenza (AI) and Newcastle disease (ND), the present study was conducted to evaluate the effects of Marek's disease (MD)-resistant breeding and vaccination against the immunosuppression induced by virulent Marek's disease virus (MDV). The results showed that haemagglutination inhibition (HI) titres to AI and ND in MDV-unchallenged groups were significantly higher than those of MDV-challenged groups (P<0.05), those of the resistant birds were significantly higher than those of the common birds (P<0.05) and those of the herpes virus of turkeys (HVT)-vaccinated birds were significantly higher than those of the HVT-unvaccinated birds (P<0.05). The results demonstrated that antibody responses to the vaccinations of AI and ND were significantly suppressed by MDV infection, and MD-resistant breeding and HVT vaccination could significantly increase resistance to the suppression.
DOI: 10.1080/03079459808419292
发表时间: 1998-04
期刊: Avian Pathology
影响因子: 2.8
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