The association of long-term alcohol biomarkers with risk for alcohol-related injury: Implications for screening.

The association of long-term alcohol biomarkers with risk for alcohol-related injury: Implications for screening.
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DOI:
10.1080/14659891.2016.1217090
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发表时间:
2017
影响因子:
0.8
通讯作者:
Fuhrmann D
Fuhrmann D
中科院分区:
医学4区
文献类型:
--
作者:
Fendrich M;Berger L;Fuhrmann D

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酒精滥用是造成严重伤害和死亡的主要危险因素。对于那些在紧急护理环境中经历创伤的人,最近的酒精滥用史通常通过自我报告措施进行评估。由于在这些情况下,报告不足可能是一个问题,因此长期生物标志物等客观指标可能有助于识别可能需要干预的危险饮酒者。认识到这一点,我们调查了(1)在来自中西部城市大学的600多名大学生的概率样本中,危险饮酒是否与酒精相关伤害的报告有关;(2)在同一样本中,升高的长期生物标志物是否显示出类似的关联。从对酒精使用障碍识别测试C(AUDIT-C)的反应以及对乙基葡萄糖醛酸苷(一种直接的酒精生物标志物)进行测试的头发和指甲中得出的相关性表明,危险饮酒与酒精相关损伤的风险升高显著相关。筛查和干预在卫生保健环境的影响进行了讨论。
Alcohol misuse is a leading risk factor for serious injury and death. For those experiencing trauma in emergency care settings, recent alcohol misuse history is typically assessed via self-report measures. Since underreporting may be a problem in these settings, objective indicators like long-term biomarkers may be useful for identifying hazardous drinkers who may need intervention. Recognizing this, we investigated (1) whether hazardous drinking was linked to reports of alcohol-related injury in a probability sample of over 600 college students from a large, Midwestern, urban university; (2) whether elevated long-term biomarkers showed similar associations in the same sample. Associations derived from responses to the Alcohol Use Disorder Identification Test-C (AUDIT-C) as well as from hair and fingernails tested for ethyl glucuronide, a direct alcohol biomarker, suggested that hazardous drinking is significantly associated with elevated risk for alcohol-related injury. Implications for screening and intervention in health care settings are discussed.
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