Men's body mass index in relation to embryo quality and clinical outcomes in couples undergoing in vitro fertilization.
Men's body mass index in relation to embryo quality and clinical outcomes in couples undergoing in vitro fertilization.
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DOI：
10.1016/j.fertnstert.2012.07.1102
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发表时间：
2012-11
影响因子：
6.7
通讯作者：
Chavarro, Jorge E.
中科院分区：
文献类型：
--
作者：
Colaci, Daniela S.;Afeiche, Myriam;Gaskins, Audrey J.;Wright, Diane L.;Toth, Thomas L.;Tanrikut, Cigdem;Hauser, Russ;Chavarro, Jorge E.
评估男性体重指数（BMI）、早期胚胎质量和接受体外受精夫妇临床结局之间的关系。前瞻性队列研究。学术医疗中心的生育诊所。114对夫妇接受了172个ART周期。无受精率、胚胎质量、种植率、临床妊娠率和活产率。在传统IVF周期中，肥胖男性的受精率高于正常体重男性（p趋势=0.04）。男性的BMI与第3天的低质量胚胎比例（p趋势=0.67），缓慢的胚胎卵裂率（p趋势=0.17）或加速的胚胎卵裂率（p趋势=0.07）之间没有显着关联。男性BMI与每次胚胎移植的β-hCG阳性率（p趋势=0.37）、临床妊娠率（p趋势=0.91）或活产率（p趋势=0.42）无关。在接受ICSI的夫妇中，肥胖男性伴侣的活产几率为84%（95% CI 10%-97%），低于BMI正常男性的几率（p趋势=0.04）。我们的数据表明，男性肥胖可能对接受ICSI的夫妇中活产的几率产生有害影响。
To evaluate the association between men’s body mass index (BMI), early embryo quality and clinical outcomes in couples undergoing in vitro fertilization. Prospective cohort study. Fertility clinic in an academic medical center. 114 couples that underwent 172 ART cycles. None Fertilization rate, embryo quality, implantation rate, clinical pregnancy rate and live birth rate. Fertilization rate was higher among obese men than among normal weight men (p-trend=0.04) in conventional IVF cycles. No significant associations were found between men’s BMI and the proportion of poor quality embryos on day 3 (p-trend =0.67), slow embryo cleavage rate (p-trend=0.17), or accelerated embryo cleavage rate (p-trend =0.07). Men’s BMI was unrelated to positive β-hCG rate (p-trend =0.37), clinical pregnancy rate (p-trend =0.91) or live birth rate (p-trend =0.42) per embryo transfer. Among couples undergoing ICSI, the odds of live birth in couples with obese male partners was 84% (95% CI 10%–97%) lower than the odds in couples with men with normal BMI (p-trend=0.04). Our data suggest a possible deleterious effect of male obesity on the odds of having a live birth among couples undergoing ICSI.
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影响因子：
3.4
作者：
Håkonsen LB;Thulstrup AM;Aggerholm AS;Olsen J;Bonde JP;Andersen CY;Bungum M;Ernst EH;Hansen ML;Ernst EH;Ramlau-Hansen CH
通讯作者：
Ramlau-Hansen CH
影响因子：
6.7
作者：
Chavarro, Jorge E.;Ehrlich, Shelley;Colaci, Daniela S.;Wright, Diane L.;Toth, Thomas L.;Petrozza, John C.;Hauser, Russ
通讯作者：
Hauser, Russ
影响因子：
2.4
作者：
Rybar, R.;Kopecka, V.;Rubes, J.
通讯作者：
Rubes, J.
影响因子：
3.1
作者：
Keltz, Julia;Zapantis, Athena;Polotsky, Alex J.
通讯作者：
Polotsky, Alex J.
影响因子：
6.1
作者：
Omland, AK;Åbyholm, T;Tanbo, T
通讯作者：
Tanbo, T