Cortical projections to the superior colliculus in tree shrews (Tupaia belangeri).
Cortical projections to the superior colliculus in tree shrews (Tupaia belangeri).
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DOI：
10.1002/cne.23249
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发表时间：
2013-05-01
影响因子：
2.5
通讯作者：
Kaas, Jon H.
中科院分区：
文献类型：
--
作者：
Baldwin, Mary K. L.;Wei, Haiyang;Reed, Jamie L.;Bickford, Martha E.;Petry, Heywood M.;Kaas, Jon H.
上丘的视觉运动功能不仅依赖于视网膜的直接输入，还依赖于新皮层的输入。由于哺乳动物在新皮层的面积组织、视觉和视觉运动区域的数量组织上各不相同，皮质顶叶投射的模式也各不相同。尤其是灵长类动物，它们有大量的视觉区域投射到上丘。由于树鼩是灵长类动物的近亲，而且它们也具有高度的视觉能力，因此我们通过向树鼩丘注射解剖示踪剂来研究树鼩上丘皮层神经元的分布。由于视觉位置组织的视觉区域的投影预计与上丘的视觉位置相匹配，因此在上丘不同的视网膜定位位置注射可以提供有关纹状体外皮层地形区域的位置和组织的信息。上丘小剂量注射标记17区（V1）和18区（V2）内的神经元，与这些区域和上丘的已知地形一致。此外，标记细胞簇在颞叶视觉皮层的独立位置为五个或更多的地形组织区域提供了证据。包括上丘深层的注射也标记了内侧额叶皮层的神经元，很可能在运动前皮层。仅偶有标记神经元在体感觉或听觉皮层中被观察到。不管示踪剂注射的位置如何，我们发现树鼩与灵长类动物不同，从后顶叶皮层向上丘的大量投射并不是树鼩的特征。
The visuomotor functions of the superior colliculus depend not only on direct inputs from the retina, but also on inputs from neocortex. As mammals vary in the areal organization of neocortex, and in the organization of the number of visual and visuomotor areas, patterns of corticotectal projections vary. Primates in particular have a large number of visual areas projecting to the superior colliculus. As tree shrews are close relatives of primates, and they are also highly visual, we studied the distribution of cortical neurons projecting to the superior colliculus by injecting anatomical tracers into the colliculus. Since projections from visuotopically organized visual areas are expected to match the visuotopy of the superior colliculus, injections at different retinotopic locations in the superior colliculus provide information about the locations and organization of topographic areas in extrastriate cortex. Small injections in the superior colliculus labeled neurons in locations within areas 17 (V1) and 18 (V2) that are consistent with the known topography of these areas and the superior colliculus. In addition, the separate locations of clusters of labeled cells in temporal visual cortex provide evidence for five or more topographically organized areas. Injections that included deeper layers of the superior colliculus also labeled neurons in medial frontal cortex, likely in premotor cortex. Only occasional labeled neurons were observed in somatosensory or auditory cortex. Regardless of tracer injection location, we found that unlike primates, a substantial projection to the superior colliculus from posterior parietal cortex is not a characteristic of tree shrews.
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DOI：
10.1523/jneurosci.1777-11.2011
发表时间：
2011-08-10
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Gharbawie OA;Stepniewska I;Qi H;Kaas JH
通讯作者：
Kaas JH
影响因子：
2.5
作者：
GRAHAM, J;LIN, CS;KAAS, JH
通讯作者：
KAAS, JH
DOI：
10.1007/bf00325634
发表时间：
1971-01-01
期刊：
ZEITSCHRIFT FUR ZELLFORSCHUNG UND MIKROSKOPISCHE ANATOMIE
影响因子：
--
作者：
GENESERJENSEN, FA;BLACKSTAD, TW
通讯作者：
BLACKSTAD, TW
影响因子：
3.7
作者：
Chomsung, Ranida D.;Wei, Haiyang;Bickford, Martha E.
通讯作者：
Bickford, Martha E.
影响因子：
2.5
作者：
Hoffer, ZS;Arantes, HB;Alloway, KD
通讯作者：
Alloway, KD