Historical survey on chromatoid body research.

Historical survey on chromatoid body research.
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DOI:
10.1267/ahc.08010
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发表时间:
2008-08-28
影响因子:
2.4
通讯作者:
Yokota S
Yokota S
中科院分区:
生物学4区
文献类型:
--
作者:
Yokota S

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拟染色体是雄性生殖细胞特有的细胞器,存在于精母细胞和精子细胞中。与CB相对应的细胞质颗粒最早是在大约130年前由von布伦于1876年发现的。30年后,德国术语“chromatoide Körper”(拟染色体体)被引入来描述这种颗粒,至今仍在使用。在这篇评论中,首先,光显微镜研究CB的第一个60年所获得的结果进行了检查。接下来,许多发现揭示了电子显微镜研究进行了审查。最后,最近的分子细胞生物学研究有关的CB进行了讨论。通过对近130年来有关CB的研究论文的分析,我们可以得出这样的结论:现代的许多分子细胞生物学研究无疑都是建立在大量早期研究积累的基础上的。
The chromatoid body (CB) is a male reproductive cell-specific organelle that appears in spermatocytes and spermatids. The cytoplasmic granule corresponding to the CB was first discovered some 130 years ago by von Brunn in 1876. Thirty years later the German term “chromatoide Körper” (chromatoid body) was introduced to describe this granule and is still used today. In this review, first, the results obtained by light microscopic studies on the CB for the first 60 years are examined. Next, many findings revealed by electron microscopic studies are reviewed. Finally, recent molecular cell biological studies concerning the CB are discussed. The conclusion obtained by exploring the papers on CB published during the past 130 years is that many of the modern molecular cell biological studies are undoubtedly based on information accumulated by vast amounts of early studies.
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