Components of the Arabidopsis nuclear pore complex play multiple diverse roles in control of plant growth.
Components of the Arabidopsis nuclear pore complex play multiple diverse roles in control of plant growth.
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DOI：
10.1093/jxb/eru346
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发表时间：
2014-11
影响因子：
6.9
通讯作者：
Parry G
中科院分区：
文献类型：
--
作者：
Parry G
核孔复合物的组分对多效性生长表型、mRNA转运和基因表达具有不同的影响，在拟南芥核孔蛋白功能的比较研究中提出。核孔复合物（NPC）是一种多亚基蛋白质聚集体，促进RNA和蛋白质在细胞核和细胞质之间的运动。关于拟南芥NPC对生长和发育的影响知之甚少。研究了拟南芥核孔蛋白突变体的幼苗发育、开花时间、核形态、mRNA积累和基因表达的变化。核出口的mRNA差异影响植物中的核孔蛋白，位于不同的NPC亚复合物的缺陷。这项研究揭示了核孔蛋白改变分子和植物生长表型的方式的差异，表明核孔亚复合物在核运输中发挥独特的作用，并揭示了核运输中涉及的基因表达之间可能的反馈关系。
Components of the nuclear pore complex have differential effects on pleiotropic growth phenotypes, mRNA transport, and gene expression, presented in a comparative study of nucleoporin function in Arabidopsis. The nuclear pore complex (NPC) is a multisubunit protein conglomerate that facilitates movement of RNA and protein between the nucleus and cytoplasm. Relatively little is known regarding the influence of the Arabidopsis NPC on growth and development. Seedling development, flowering time, nuclear morphology, mRNA accumulation, and gene expression changes in Arabidopsis nucleoporin mutants were investigated. Nuclear export of mRNA is differentially affected in plants with defects in nucleoporins that lie in different NPC subcomplexes. This study reveals differences in the manner by which nucleoporins alter molecular and plant growth phenotypes, suggesting that nuclear pore subcomplexes play distinct roles in nuclear transport and reveal a possible feedback relationship between the expression of genes involved in nuclear transport.
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DOI：
10.1074/mcp.m900038-mcp200
发表时间：
2009-09
期刊：
Molecular & cellular proteomics : MCP
影响因子：
--
作者：
DeGrasse JA;DuBois KN;Devos D;Siegel TN;Sali A;Field MC;Rout MP;Chait BT
通讯作者：
Chait BT
影响因子：
11.4
作者：
Krull, Sandra;Doerries, Julia;Boysen, Bjoern;Reidenbach, Sonja;Magnius, Lars;Norder, Helene;Thyberg, Johan;Cordes, Volker C.
通讯作者：
Cordes, Volker C.
DOI：
10.1083/jcb.201109008
发表时间：
2012-02-20
期刊：
The Journal of cell biology
影响因子：
--
作者：
Fernandez-Martinez J;Phillips J;Sekedat MD;Diaz-Avalos R;Velazquez-Muriel J;Franke JD;Williams R;Stokes DL;Chait BT;Sali A;Rout MP
通讯作者：
Rout MP
影响因子：
5.3
作者：
Baï, SW;Rouquette, J;Doye, V
通讯作者：
Doye, V
影响因子：
5.3
作者：
Dong, Chun-Hai;Hu, Xiangyang;Zhu, Jian-Kang
通讯作者：
Zhu, Jian-Kang