Association of working shifts, inside and outside of healthcare, with severe COVID-19: an observational study.
Association of working shifts, inside and outside of healthcare, with severe COVID-19: an observational study.
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DOI：
10.1186/s12889-021-10839-0
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发表时间：
2021-04-22
影响因子：
4.5
通讯作者：
Khunti K
中科院分区：
文献类型：
--
作者：
Rowlands AV;Gillies C;Chudasama Y;Davies MJ;Islam N;Kloecker DE;Lawson C;Pareek M;Razieh C;Zaccardi F;Yates T;Khunti K
健康和关键工作人员患上严重COVID-19的几率增加;然而，尚不清楚这种情况是否会在工作模式不规律的人中加剧。我们的目标是调查健康和轮班工人患上严重COVID-19的几率。我们纳入了基线（2006年至2010年）的就业或自雇英国生物银行参与者，并与截至2020年8月31日的COVID-19数据相关联。参与者在基线时被分组为既不是卫生工作者也不是轮班工作者（参考类别），仅是卫生工作者，仅是轮班工作者，或两者兼而有之，并在logistic回归中研究了与严重COVID-19的关联。在235，685名参与者中（81.5%既不是健康也不是轮班工作者，1.4%只是卫生工作者，16.9%只是轮班工作者，0.3%两者），有580例（0.25%）严重COVID-19病例。在卫生工作者中，重度COVID-19的几率更高（调整后的比值比：2.32 [95% CI：1.33，4.05];轮班工作者（2.06 [1.72，2.47]）;轮班工作的卫生工作者（7.56 [3.86，14.79]）。与白色个体相比，在南亚、黑人和非洲加勒比民族中，既是卫生工作者又是轮班工作者对严重COVID-19的几率可能有更大的影响。健康和轮班工作（在2006-2010年基线测量）与2020年严重COVID-19的几率增加一倍以上独立相关;轮班工作的卫生工作者的几率高出7倍以上。疫苗接种、治疗和预防选择不仅应考虑到健康和关键工人的身份，还应考虑到轮班工人的身份。在线版本包含补充材料，可通过10.1186/s12889-021-10839-0获得。
Health and key workers have elevated odds of developing severe COVID-19; it is not known, however, if this is exacerbated in those with irregular work patterns. We aimed to investigate the odds of developing severe COVID-19 in health and shift workers. We included UK Biobank participants in employment or self-employed at baseline (2006–2010) and with linked COVID-19 data to 31st August 2020. Participants were grouped as neither a health worker nor shift worker (reference category) at baseline, health worker only, shift worker only, or both, and associations with severe COVID-19 investigated in logistic regressions. Of 235,685 participants (81·5% neither health nor shift worker, 1·4% health worker only, 16·9% shift worker only, and 0·3% both), there were 580 (0·25%) cases of severe COVID-19. The odds of severe COVID-19 was higher in health workers (adjusted odds ratio: 2·32 [95% CI: 1·33, 4·05]; shift workers (2·06 [1·72, 2·47]); and in health workers who worked shifts (7·56 [3·86, 14·79]). Being both a health worker and a shift worker had a possible greater impact on the odds of severe COVID-19 in South Asian and Black and African Caribbean ethnicities compared to White individuals. Both health and shift work (measured at baseline, 2006–2010) were independently associated with over twice the odds of severe COVID-19 in 2020; the odds were over seven times higher in health workers who work shifts. Vaccinations, therapeutic and preventative options should take into consideration not only health and key worker status but also shift worker status. The online version contains supplementary material available at 10.1186/s12889-021-10839-0.
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DOI：
10.1136/bmj.m3582
发表时间：
2020-10-28
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Shah ASV;Wood R;Gribben C;Caldwell D;Bishop J;Weir A;Kennedy S;Reid M;Smith-Palmer A;Goldberg D;McMenamin J;Fischbacher C;Robertson C;Hutchinson S;McKeigue P;Colhoun H;McAllister DA
通讯作者：
McAllister DA
影响因子：
10
作者：
Hopkinson, Nicholas S.;Rossi, Niccolo;Falchi, Mario
通讯作者：
Falchi, Mario
影响因子：
8.9
作者：
Rowlands AV;Kloecker DE;Chudasama Y;Davies MJ;Dawkins NP;Edwardson CL;Gillies C;Khunti K;Razieh C;Islam N;Zaccardi F;Yates T
通讯作者：
Yates T
影响因子：
15.8
作者：
Sudlow C;Gallacher J;Allen N;Beral V;Burton P;Danesh J;Downey P;Elliott P;Green J;Landray M;Liu B;Matthews P;Ong G;Pell J;Silman A;Young A;Sprosen T;Peakman T;Collins R
通讯作者：
Collins R
影响因子：
6.3
作者：
Tenkanen, L;Sjoblom, T;Harma, M
通讯作者：
Harma, M