Salivary glucose concentration and excretion in normal and diabetic subjects.
Salivary glucose concentration and excretion in normal and diabetic subjects.
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DOI：
10.1155/2009/430426
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发表时间：
2009
影响因子：
--
通讯作者：
Sener A
中科院分区：
文献类型：
--
作者：
Jurysta C;Bulur N;Oguzhan B;Satman I;Yilmaz TM;Malaisse WJ;Sener A
本报告的主要目的是重新评估唾液葡萄糖的浓度和分泌的非刺激和机械刺激唾液在正常和糖尿病受试者。在正常受试者中，唾液葡萄糖浓度降低，唾液流量增加，但葡萄糖排泄量不变 当比较刺激的唾液与未刺激的唾液时，记录速率。在糖尿病患者中，在相同的实验条件下观察到唾液流量增加，唾液葡萄糖浓度和葡萄糖排泄率不变。唾液葡萄糖浓度和排泄量在糖尿病患者中比对照组高得多，无论是在未刺激或刺激的唾液中。在糖尿病患者中，无论是在非刺激还是刺激的唾液中，均未发现唾液中葡萄糖浓度或葡萄糖排泄率与唾液中葡萄糖浓度或葡萄糖排泄率之间存在显著相关性。在后一种患者中，与对照组相比，唾液葡萄糖浓度增加的相对幅度与血糖浓度增加的相对幅度相当。这两个变量之间的关系也记录在正常受试者和糖尿病患者进行口服葡萄糖耐量试验。
The present report aims mainly at a reevaluation of salivary glucose concentration and excretion in unstimulated and mechanically stimulated saliva in both normal and diabetic subjects. In normal subjects, a decrease in saliva glucose concentration, an increase in salivary flow, but an unchanged glucose excretion rate were recorded when comparing stimulated saliva to unstimulated saliva. In diabetic patients, an increase in salivary flow with unchanged salivary glucose concentration and glucose excretion rate were observed under the same experimental conditions. Salivary glucose concentration and excretion were much higher in diabetic patients than in control subjects, whether in unstimulated or stimulated saliva. No significant correlation between glycemia and either glucose concentration or glucose excretion rate was found in the diabetic patients, whether in unstimulated or stimulated saliva. In the latter patients, as compared to control subjects, the relative magnitude of the increase in saliva glucose concentration was comparable, however, to that of blood glucose concentration. The relationship between these two variables was also documented in normal subjects and diabetic patients undergoing an oral glucose tolerance test.
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影响因子：
4.4
作者：
DEJONG, MH;VANDERHOEVEN, JS;OLIJVE, JH
通讯作者：
OLIJVE, JH
影响因子：
7.6
作者：
BENARYEH, H;MIRON, D;GUTMAN, D
通讯作者：
GUTMAN, D
影响因子：
7.6
作者：
GOULET, D;BRUDEVOLD, F;ATTARZADEH, F
通讯作者：
ATTARZADEH, F
影响因子：
4.3
作者：
Mata, AD;Marques, D;Singh, J
通讯作者：
Singh, J
影响因子：
17.3
作者：
FORBAT, LN;COLLINS, RE;SONKSEN, PH
通讯作者：
SONKSEN, PH