Estimated incidence of influenza-associated severe acute respiratory infections in Indonesia, 2013-2016.

Estimated incidence of influenza-associated severe acute respiratory infections in Indonesia, 2013-2016.
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DOI:
10.1111/irv.12496
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发表时间:
2018-01
影响因子:
4.4
通讯作者:
Setiawaty V
Setiawaty V
中科院分区:
医学4区
文献类型:
--
作者:
Susilarini NK;Haryanto E;Praptiningsih CY;Mangiri A;Kipuw N;Tarya I;Rusli R;Sumardi G;Widuri E;Sembiring MM;Noviyanti W;Widaningrum C;Lafond KE;Samaan G;Setiawaty V

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印度尼西亚以医院为基础的严重急性呼吸道感染(SARI)监测系统,即印度尼西亚监测系统(SIBI),于2013年建立。虽然严重急性呼吸道感染等呼吸道疾病构成严重问题,但印度尼西亚基于发病率的流感疾病负担数据有限。本研究旨在估计2013 - 2016年印度尼西亚三个现有SIBI监测点流感相关严重急性呼吸道感染的发病率。从2013年5月至2016年4月,对印度尼西亚三个地区(Gunung Kidul、Balikpapan、Deli Serdang)哨点医院的住院患者进行了急性呼吸道感染筛查。从符合条件的住院病人收集呼吸道标本,并进行流感病毒筛查。以这些SIBI登记的流感阳性急性呼吸道感染病例为分子,以住院调查(HAS)确定的集水区人口为分母,计算年发病率,以确定哨点地区医院按年龄呼吸道编码的入院人数。2013年5月至2016年4月,共登记了1527例急性呼吸道感染病例,其中1392例(91%)进行了标本检测,199例(14%)呈流感阳性。流感相关严重急性呼吸道感染的年总体估计发病率为每10万人13至19例。发病率最高的是0 ~ 4岁儿童(每10万人82 ~ 114人),其次是5 ~ 14岁儿童(每10万人22 ~ 36人)。这些地区与流感相关的严重急性呼吸道感染发病率表明,印度尼西亚幼儿流感住院负担沉重。需要进一步研究其他潜在风险群体(如孕妇和老年人)的流感负担。
Indonesia's hospital‐based Severe Acute Respiratory Infection (SARI) surveillance system, Surveilans Infeksi Saluran Pernafasan Akut Berat Indonesia (SIBI), was established in 2013. While respiratory illnesses such as SARI pose a significant problem, there are limited incidence‐based data on influenza disease burden in Indonesia. This study aimed to estimate the incidence of influenza‐associated SARI in Indonesia during 2013‐2016 at three existing SIBI surveillance sites. From May 2013 to April 2016, inpatients from sentinel hospitals in three districts of Indonesia (Gunung Kidul, Balikpapan, Deli Serdang) were screened for SARI. Respiratory specimens were collected from eligible inpatients and screened for influenza viruses. Annual incidence rates were calculated using these SIBI‐enrolled influenza‐positive SARI cases as a numerator, with a denominator catchment population defined through hospital admission survey (HAS) to identify respiratory‐coded admissions by age to hospitals in the sentinel site districts. From May 2013 to April 2016, there were 1527 SARI cases enrolled, of whom 1392 (91%) had specimens tested and 199 (14%) were influenza‐positive. The overall estimated annual incidence of influenza‐associated SARI ranged from 13 to 19 per 100 000 population. Incidence was highest in children aged 0‐4 years (82‐114 per 100 000 population), followed by children 5‐14 years (22‐36 per 100 000 population). Incidence rates of influenza‐associated SARI in these districts indicate a substantial burden of influenza hospitalizations in young children in Indonesia. Further studies are needed to examine the influenza burden in other potential risk groups such as pregnant women and the elderly.
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发表时间: 2012-10-01
期刊: Bulletin of the World Health Organization: International Journal of Public Health
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