Association between myopia progression and quantity of laser treatment for retinopathy of prematurity.
Association between myopia progression and quantity of laser treatment for retinopathy of prematurity.
复制标题
DOI：
10.1371/journal.pone.0279898
复制
发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
Costakos, Deborah M.
中科院分区：
文献类型：
--
作者：
Hwang, Eileen S.;Kassem, Iris S.;Allozi, Rawan;Kravets, Sasha;Al-Kirwi, Khalid Y.;Hallak, Joelle A.;Costakos, Deborah M.
先前的研究发现，患有早产儿视网膜病变(ROP)的婴儿，如果接受更多的后部疾病的治疗，并有更多的激光斑点，则会出现更高的近视。这些研究包括激光密度不同的多名医生。在单一医生的治疗中，激光光斑计数是无血管视网膜面积和疾病前后位置的更好替代，因此可以更好地评估与近视的关系。我们的回顾性研究包括由单一中心的一位外科医生用激光治疗ROP的婴儿。排除标准为激光治疗过程中出现的不规则性和ROP的附加治疗。我们使用线性混合效应模型评估了激光光斑计数和屈光不正随时间变化之间的相关性。我们对78例153只眼进行了激光治疗ROP。平均出生胎龄25.3±1.8周，出生体重737±248g，激光光斑计数1793±728，治疗后随访37±29个月。矫正年龄0~1岁平均等值球镜+0.4±2.3度，1~2岁平均-1.3±3.2D，2~3岁平均-0.8±3.1D。接受更多激光光斑的眼睛随着时间的推移屈光不正的变化明显更大(每1000个光点每年近视增加0.30D)。远视眼在18个月前在随访期内无一例发生近视。随着时间的推移，激光治疗ROP到更大的无血管视网膜区域的婴儿会出现更大的近视。
Previous studies found that infants with retinopathy of prematurity (ROP) who were treated for more posterior disease with a greater number of laser spots developed higher myopia. These studies included multiple physicians with variations in laser density. In treatments by a single physician, laser spot count is a better surrogate for area of avascular retina and anterior-posterior location of disease, so that the relationship with myopia can be better assessed. Our retrospective study included infants treated with laser for ROP by a single surgeon at a single center. Exclusion criteria were irregularities during laser and additional treatment for ROP. We assessed correlation between laser spot count and change in refractive error over time using a linear mixed effects model. We studied 153 eyes from 78 subjects treated with laser for ROP. The average gestational age at birth was 25.3±1.8 weeks, birth weight 737±248 grams, laser spot count 1793±728, and post-treatment follow up 37±29 months. Between corrected ages 0–1 years, the mean spherical equivalent was +0.4±2.3 diopters; between ages 1–2, it was -1.3±3.2D; and ages 2–3 was -0.8±3.1D. Eyes that received more laser spots had significantly greater change in refractive error over time (0.30D more myopia per year per 1000 spots). None of the eyes with hyperopia before 18 months developed myopia during the follow-up period. Greater myopia developed over time in infants with ROP treated by laser to a larger area of avascular retina.
登录
查看更多内容
影响因子：
1.6
作者：
Dikopf, Mark S.;Machen, Lindsay A.;Kassem, Iris S.
通讯作者：
Kassem, Iris S.
影响因子：
1.6
作者：
Quinn, Graham E.;Dobson, Velma;Good, William V.
通讯作者：
Good, William V.
影响因子：
3.9
作者：
Mori, Yujiro;Arima, Mitsuru;Sonoda, Koh-Hei
通讯作者：
Sonoda, Koh-Hei
影响因子：
1.8
作者：
LUE, CL;HANSEN, RM;FULTON, AB
通讯作者：
FULTON, AB
影响因子：
13.7
作者：
Quinn, GE;Dobson, V;Stone, RA
通讯作者：
Stone, RA