The Genomedata format for storing large-scale functional genomics data.

The Genomedata format for storing large-scale functional genomics data.
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DOI:
10.1093/bioinformatics/btq164
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发表时间:
2010-06-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
通讯作者:
Noble WS
Noble WS
中科院分区:
其他
文献类型:
--
作者:
Hoffman MM;Buske OJ;Noble WS

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摘要:我们提出了一种格式,用于有效存储锚定在基因组上的多个数字数据轨道。这种格式允许对数百gb的数据进行快速随机访问,同时保留很小的磁盘空间占用。我们还开发了将数据加载为这种格式的实用程序。我们表明,从这种格式检索数据比使用wiggle文件的简单方法快2900倍以上。可用性和实现:在GNU通用公共许可证下,可在http://noble.gs.washington.edu/proj/genomedata/上获得Python和C组件的参考实现。联系人:william-noble@uw.edu
Summary: We present a format for efficient storage of multiple tracks of numeric data anchored to a genome. The format allows fast random access to hundreds of gigabytes of data, while retaining a small disk space footprint. We have also developed utilities to load data into this format. We show that retrieving data from this format is more than 2900 times faster than a naive approach using wiggle files. Availability and Implementation: Reference implementation in Python and C components available at http://noble.gs.washington.edu/proj/genomedata/ under the GNU General Public License. Contact: william-noble@uw.edu
UCSC基因组浏览器数据库:更新2010。
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影响因子: 14.9
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