Heroin and Methamphetamine Injection: An Emerging Drug Use Pattern.
Heroin and Methamphetamine Injection: An Emerging Drug Use Pattern.
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DOI：
10.1080/10826084.2016.1271432
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发表时间：
2017-07-03
影响因子：
2
通讯作者：
Raville L
中科院分区：
文献类型：
--
作者：
Al-Tayyib A;Koester S;Langegger S;Raville L
我们试图描述一种以注射甲基苯丙胺和海洛因为特征的新兴药物使用模式。我们通过人口统计学、注射行为、HIV和HCV状态以及药物过量来检查药物注射模式的差异。注射吸毒者（PWID）被招募为科罗拉多州丹佛市国家艾滋病毒行为监测（NHBS）系统的一部分。我们使用卡方统计来评估仅注射海洛因、仅注射甲基苯丙胺和联合注射海洛因和甲基苯丙胺的患者之间的差异。我们使用广义线性模型来估计未调整和调整的患病率，以描述2015年药物注射方式与报告的非致命性过量用药之间的关系。我们还研究了2005年、2009年和2012年之前NHBS周期中最常注射的药物的变化。在2015年完成调查的592名参与者中，173人（29.2%）报告仅注射海洛因，123人（20.8%）报告仅注射甲基苯丙胺，296人（50.0%）报告在过去12个月内注射了两种药物。与仅注射海洛因相比，注射海洛因和甲基苯丙胺与过去12个月报告的过量用药增加2.8倍（95%可信区间：1.7,4.5）有关。报告甲基苯丙胺为最常注射毒品的比例从2005年的2.1%上升到2015年的29.6% （p < 0.001）。甲基苯丙胺注射的迅速增加以及甲基苯丙胺与海洛因混合的出现可能对公共卫生产生严重影响。
We sought to describe an emerging drug use pattern characterized by injection of both methamphetamine and heroin. We examined differences in drug injection patterns by demographics, injection behaviors, HIV and HCV status, and overdose. Persons who inject drugs (PWID) were recruited as part of the National HIV Behavioral Surveillance (NHBS) system in Denver, Colorado. We used chi-square statistics to assess differences between those who reported only heroin injection, only methamphetamine injection, and combined heroin and methamphetamine injection. We used generalized linear models to estimate unadjusted and adjusted prevalence ratios to describe the association between drug injection pattern and reported nonfatal overdose in 2015. We also examined changes in the drug reported as most frequently injected across previous NHBS cycles from 2005, 2009, and 2012. Of 592 participants who completed the survey in 2015, 173 (29.2%) reported only injecting heroin, 123 (20.8%) reported only injecting methamphetamine, and 296 (50.0%) reported injecting both drugs during the past 12 months. Injecting both heroin and methamphetamine was associated with a 2.8 (95% confidence interval: 1.7, 4.5) fold increase in reported overdose in the past 12 months compared with only injecting heroin. The proportion of those reporting methamphetamine as the most frequently injected drug increased from 2.1% in 2005 to 29.6% in 2015 (p < 0.001). The rapid increase in methamphetamine injection, and the emergence of combining methamphetamine with heroin, may have serious public health implications.
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影响因子：
3.8
作者：
Hopper, K;Barrow, SM
通讯作者：
Barrow, SM
在加利福尼亚州圣地亚哥注射毒品的人中，毒品使用，危险行为和健康状况的模式：潜在的阶级分析。
影响因子：
2
作者：
Roth AM;Armenta RA;Wagner KD;Roesch SC;Bluthenthal RN;Cuevas-Mota J;Garfein RS
通讯作者：
Garfein RS
影响因子：
4.2
作者：
Ochoa, KC;Davidson, PJ;Moss, AR
通讯作者：
Moss, AR
影响因子：
2
作者：
Meacham MC;Rudolph AE;Strathdee SA;Rusch ML;Brouwer KC;Patterson TL;Vera A;Rangel G;Roesch SC
通讯作者：
Roesch SC
影响因子：
4.2
作者：
Bluthenthal, Ricky N.;Wenger, Lynn;Kral, Alex H.
通讯作者：
Kral, Alex H.