Patterns of drug use, risky behavior, and health status among persons who inject drugs living in San Diego, California: a latent class analysis.
Patterns of drug use, risky behavior, and health status among persons who inject drugs living in San Diego, California: a latent class analysis.
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在加利福尼亚州圣地亚哥注射毒品的人中，毒品使用，危险行为和健康状况的模式：潜在的阶级分析。
DOI：
10.3109/10826084.2014.962661
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发表时间：
2015-01
影响因子：
2
通讯作者：
Garfein RS
中科院分区：
文献类型：
--
作者：
Roth AM;Armenta RA;Wagner KD;Roesch SC;Bluthenthal RN;Cuevas-Mota J;Garfein RS
在注射毒品者中，多种毒品使用（顺序或同时混合多种毒品/酒精的做法）增加了艾滋病毒传播和意外过量死亡的风险。研究表明，当地毒品市场影响毒品使用做法。然而，在以黑焦油海洛因和甲基苯丙胺为主的市场，如美国西部，对药物混合的影响知之甚少。通过一项正在进行的纵向研究收集数据，研究PWID中的药物使用，风险行为和健康状况。使用潜在类别分析（LCA）来识别通过多种给药途径（注射、吸烟和吞咽）的物质使用模式（海洛因、甲基苯丙胺、处方药、酒精和大麻）。Logistic回归分析用于确定与药物使用类别相关的行为和健康指标。样本包括511名主要为白色（51.5%）的男性（73.8%），平均年龄为43.5岁。两类不同的吸毒者占主导地位：通过多种途径使用甲基苯丙胺（51%）和注射海洛因（49%）。在多变量逻辑回归分析中，班级成员资格与年龄、种族和住房状况相关。艾滋病毒血清反应阳性并报告先前性传播感染的PWID属于甲基苯丙胺类的几率增加。那些HCV阳性并报告先前阿片类药物过量的人主要是海洛因注射类的几率增加（所有P值<0.05）。主要注射海洛因的PWID与使用甲基苯丙胺的PWID之间的风险行为和健康结果不同。研究结果表明，在PWID主要使用黑焦油海洛因或甲基苯丙胺的地区，针对PWID亚群的干预措施可以提高有效性。
Among persons who inject drugs (PWID), polydrug use (the practice of mixing multiple drugs/alcohol sequentially or simultaneously) increases risk for HIV transmission and unintentional overdose deaths. Research has shown local drug markets influence drug use practices. However, little is known about the impact of drug mixing in markets dominated by black tar heroin and methamphetamine, such as the western United States. Data were collected through an ongoing longitudinal study examining drug use, risk behavior, and health status among PWID. Latent class analysis (LCA) was used to identify patterns of substance use (heroin, methamphetamine, prescription drugs, alcohol, and marijuana) via multiple administration routes (injecting, smoking, and swallowing). Logistic regression was used to identify behaviors and health indicators associated with drug use class. The sample included 511 mostly white (51.5%) males (73.8%), with mean age of 43.5 years. Two distinct classes of drug users predominated: methamphetamine by multiple routes (51%) and heroin by injection (49%). In multivariable logistic regression, class membership was associated with age, race, and housing status. PWID who were HIV-seropositive and reported prior sexually transmitted infections had increased odds of belonging to the methamphetamine class. Those who were HCV positive and reported previous opioid overdose had an increased odds of being in the primarily heroin injection class (all P-values < .05). Risk behaviors and health outcomes differed between PWID who primarily inject heroin vs. those who use methamphetamine. The findings suggest that in a region where PWID mainly use black tar heroin or methamphetamine, interventions tailored to sub-populations of PWID could improve effectiveness.
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影响因子：
6
作者：
Coffin, PO;Galea, S;Tardiff, K
通讯作者：
Tardiff, K
DOI：
10.1093/jurban/jth112
发表时间：
2004-06-01
影响因子：
6.6
作者：
Garfein, RS;Monterroso, ER;Holmberg, SD
通讯作者：
Holmberg, SD
影响因子：
2.9
作者：
Patra, Jayadeep;Fischer, Benedikt;Rehm, Juergen
通讯作者：
Rehm, Juergen
影响因子：
4.4
作者：
Rosenblum, Daniel;Unick, George Jay;Ciccarone, Daniel
通讯作者：
Ciccarone, Daniel
影响因子：
3
作者：
GIBSON, WA
通讯作者：
GIBSON, WA