Modularity: genes, development and evolution.

Modularity: genes, development and evolution.
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DOI:
10.1146/annurev-ecolsys-121415-032409
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发表时间:
2016
期刊:
Annual review of ecology, evolution, and systematics
影响因子:
--
通讯作者:
Marroig G
Marroig G
中科院分区:
其他
文献类型:
--
作者:
Melo D;Porto A;Cheverud JM;Marroig G

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模块化已成为进化生物学的核心概念,为该领域提供了有机结构和变异的理论。该理论重新构建了长期存在的问题,并成为遗传学、发育生物学和多元进化的统一概念框架。系统生物学和定量遗传学的研究项目正在缩小这些领域之间的差距。在这种综合正在进行的同时,一些主要主题已经出现,模块化的经验证据也变得丰富。在这篇综述中,我们从历史的角度看待模块化,强调其在生物组织不同层面的意义以及可用于检测它的不同方法。然后,我们探讨模块化定量遗传学方法与发育遗传学研究之间的关系。最后,我们研究了模块化和适应性景观之间的动态关系,以及它如何潜在地塑造进化,并有助于弥合微观和宏观进化之间的差距。
Modularity has emerged as a central concept for evolutionary biology, providing the field with a theory of organismal structure and variation. This theory has reframed long standing questions and serves as a unified conceptual framework for genetics, developmental biology and multivariate evolution. Research programs in systems biology and quantitative genetics are bridging the gap between these fields. While this synthesis is ongoing, some major themes have emerged and empirical evidence for modularity has become abundant. In this review, we look at modularity from an historical perspective, highlighting its meaning at different levels of biological organization and the different methods that can be used to detect it. We then explore the relationship between quantitative genetic approaches to modularity and developmental genetic studies. We conclude by investigating the dynamic relationship between modularity and the adaptive landscape and how this potentially shapes evolution and can help bridge the gap between micro- and macroevolution.
DOI: 10.2307/2405824
发表时间: 1960-01-01
期刊: EVOLUTION
影响因子: 3.3
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通讯作者: BERG, RL
DOI: 10.1590/s1415-47572007000300027
发表时间: 2007-03-01
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