NIH working group report: Innovative research to improve maintenance of weight loss.

NIH working group report: Innovative research to improve maintenance of weight loss.
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DOI:
10.1002/oby.20967
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发表时间:
2015-01
期刊:
Obesity (Silver Spring, Md.)
影响因子:
--
通讯作者:
Ryan D
Ryan D
中科院分区:
其他
文献类型:
--
作者:
MacLean PS;Wing RR;Davidson T;Epstein L;Goodpaster B;Hall KD;Levin BE;Perri MG;Rolls BJ;Rosenbaum M;Rothman AJ;Ryan D

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美国国立卫生研究院由国家心肺血液研究所牵头,组织了一个专家工作组,讨论减肥后体重反弹的问题。许多综合生理学和行为心理学的专家聚集在一起,目的是将他们对科学进步障碍的观点和开发改善肥胖治疗长期结果的新方法的观点融合在一起。该工作组的具体目标是:(1)确定使保持体重减轻如此困难的挑战;(2)审查在以前的研究中用于提高成功率的策略;(3)推荐新的解决方案,可以在未来的长期体重控制研究中进行检查。成功减肥的具体障碍包括对促进体重恢复的行为方案和生理适应的坚持性差。更好地了解这些行为和生理障碍是如何相关的,它们在个体之间是如何变化的,以及如何克服它们,将有助于开发新的策略,改善结果。生理和行为研究人员之间需要更多的合作和交流,以推动科学发展,并制定更好的减肥维持策略。
The National Institutes of Health, led by the National Heart, Lung, and Blood Institute, organized a working group of experts to discuss the problem of weight regain after weight loss. A number of experts in integrative physiology and behavioral psychology were convened with the goal of merging their perspectives regarding the barriers to scientific progress and the development of novel ways to improve long-term outcomes in obesity therapeutics. The specific objectives of this working group were to: (1) identify the challenges that make maintaining a reduced weight so difficult; (2) review strategies that have been used to improve success in previous studies; and (3) recommend novel solutions that could be examined in future studies of long-term weight control. Specific barriers to successful weight loss maintenance include poor adherence to behavioral regimens and physiological adaptations that promote weight regain. A better understanding of how these behavioral and physiological barriers are related, how they vary between individuals, and how they can be overcome will lead to the development of novel strategies with improved outcomes. Greater collaboration and cross-talk between physiological and behavioral researchers is needed to advance the science and develop better strategies for weight loss maintenance.
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