Neural Circuit Motifs in Valence Processing.
Neural Circuit Motifs in Valence Processing.
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DOI:
10.1016/j.neuron.2018.10.001
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发表时间:
2018-10-24
期刊:
影响因子:
16.2
通讯作者:
Tye KM
中科院分区:
文献类型:
--
作者:
Tye KM
How do our brains determine whether something is good or bad? How is this computational goal implemented in biological systems? Given the critical importance of valence processing for survival, the brain has evolved multiple strategies to solve this problem at different levels. The psychological concept of “emotional valence” is now beginning to find grounding in neuroscience. This review aims to bridge the gap between psychology and neuroscience on the topic of emotional valence processing. Here, I highlight a subset of studies that exemplify circuit motifs that repeatedly appear as implementational systems in valence processing. The motifs I identify as being important in valence processing include: 1) Labeled lines, 2) Divergent Paths, 3) Opposing Components, and 4) Neuromodulatory Gain. Importantly, the functionality of neural substrates in valence processing is dynamic, context-dependent, and changing across short and long time scales due to synaptic plasticity, competing mechanisms, and homeostatic need. Tye revisits the theoretical concept of valence originating from psychology to the investigation of valence processing in neuroscience. Tye identifies several neural circuit motifs for valence processing to provide a conceptual framework for valence processing on the implementational level.
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期刊:
JOURNAL OF ABNORMAL AND SOCIAL PSYCHOLOGY
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通讯作者:
Tye KM