Real-time tracking of self-reported symptoms to predict potential COVID-19.

Real-time tracking of self-reported symptoms to predict potential COVID-19.
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DOI:
10.1038/s41591-020-0916-2
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发表时间:
2020-07
期刊:
影响因子:
82.9
通讯作者:
Spector TD
Spector TD
中科院分区:
医学1区
文献类型:
--
作者:
Menni C;Valdes AM;Freidin MB;Sudre CH;Nguyen LH;Drew DA;Ganesh S;Varsavsky T;Cardoso MJ;El-Sayed Moustafa JS;Visconti A;Hysi P;Bowyer RCE;Mangino M;Falchi M;Wolf J;Ourselin S;Chan AT;Steves CJ;Spector TD

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在一款基于智能手机的应用程序上,共有2618862名参与者报告了他们的COVID-19潜在症状。在接受SARS-CoV-2检测的18401名参与者中,检测结果为阳性的参与者(7178人中有4668人,65.03%)报告嗅觉和味觉丧失的比例高于检测结果为阴性的参与者(11223人中有2436人,21.71%)(优势比= 6.74;95%置信区间= 6.31-7.21)。对所有报告症状的应用程序用户(805753人)的数据应用了结合症状预测可能感染的模型,预测140312人(17.42%)可能感染COVID-19。
A total of 2,618,862 participants reported their potential symptoms of COVID-19 on a smartphone-based app. Among the 18,401 who had undergone a SARS-CoV-2 test, the proportion of participants who reported loss of smell and taste was higher in those with a positive test result (4,668 of 7,178 individuals; 65.03%) than in those with a negative test result (2,436 of 11,223 participants; 21.71%) (odds ratio = 6.74; 95% confidence interval = 6.31–7.21). A model combining symptoms to predict probable infection was applied to the data from all app users who reported symptoms (805,753) and predicted that 140,312 (17.42%) participants are likely to have COVID-19.
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