The structure and usage of female and male mouse ultrasonic vocalizations reveal only minor differences.
The structure and usage of female and male mouse ultrasonic vocalizations reveal only minor differences.
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DOI：
10.1371/journal.pone.0041133
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Fischer J
中科院分区：
文献类型：
--
作者：
Hammerschmidt K;Radyushkin K;Ehrenreich H;Fischer J
在使用人类疾病小鼠模型的研究中，小鼠的超声发声（USV）越来越被认为是信息量的因变量。虽然幼犬的发声主要是为了与母亲重新建立联系，但成年雄性的“歌声”被认为是求爱信号。或者，小鼠USV通常可以用作领土信号。为了区分这两种假设，我们比较了结构和使用的成年男性和女性USV分期居民入侵者的遭遇。如果呼叫功能主要是求偶信号，男性应该比女性反应更强烈，特别是当女性入侵者出现时。反驳这一假设，我们发现，在回应女性入侵者时，女性比男性呼叫更多（228±32次呼叫/min vs. 71±15次呼叫/min），男性比男性入侵者呼叫更多（14±7.5次呼叫/min）。雌性和雄性的叫声的声学特征没有显著差异。为了控制入侵者的行为对呼叫的影响，我们使用麻醉的入侵者重复了实验。同样，雌性比雄性入侵者发出更多的呼叫（173±17呼叫/min vs. 71±15呼叫/min），而雄性比雄性入侵者发出更多的呼叫（39±17呼叫/min），并且雌性和雄性呼叫没有声学差异。的声乐活动没有显着不同的入侵者状态（清醒或麻醉），而声学结构表现出显着差异。总的来说，我们的研究结果支持这样的观点，即电话并不主要作为求偶信号，虽然他们可能服务于领土（性别独立）和求偶功能。对清醒与麻醉入侵者的反应的比较表明，后者足以引起声音活动。然而，细微的声学差异表明受试者区分了入侵者状态。
Ultrasonic vocalizations (USV) of mice are increasingly recognized as informative dependent variables in studies using mouse models of human diseases. While pup vocalizations primarily serve to re-establish contact with the mother, adult male “songs” were considered to be courtship signals. Alternatively, mouse USVs may generally function as territorial signals. To distinguish between these two hypotheses, we compared the structure and usage of adult male and female USVs in staged resident-intruder encounters. If calls function primarily as courtship signals, males should respond stronger than females, specifically when presented with a female intruder. Refuting this hypothesis, we found that in response to female intruders, females called more than males (228±32 calls/min vs. 71±15 calls/min), and males called more to female than to male intruders (14±7.5 calls/min). There were no significant differences in the acoustic characteristics of the calls given by females and males. To control for the influence of the intruder's behavior on calling, we repeated the experiments using anaesthetized intruders. Again, females produced more calls to female than male intruders (173±17 calls/min vs. 71±15 calls/min), while males called more in response to female than male intruders (39±17 calls/min), and there were no acoustic differences in female and male calls. The vocal activity did not differ significantly with regard to intruder state (awake or anaesthetized), while the acoustic structure exhibited significant differences. Taken together, our findings support the view that calls do not mainly function as courtship signals, although they might serve both a territorial (sex-independent) and a courtship function. The comparison of responses to awake vs. anaesthetized intruders suggests that the latter are sufficient to elicit vocal activity. The subtle acoustic differences, however, indicate that the subject differentiates between intruder states.
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DOI：
10.1196/annals.1298.012
发表时间：
2004-01-01
期刊：
BEHAVIORAL NEUROBIOLOGY OF BIRDSONG
影响因子：
--
作者：
Nowicki, S;Searcy, WA
通讯作者：
Searcy, WA
影响因子：
2.6
作者：
Brudzynski, SM
通讯作者：
Brudzynski, SM
影响因子：
2.6
作者：
Ehret, G
通讯作者：
Ehret, G
影响因子：
1.9
作者：
D'Amato, FR;Moles, A
通讯作者：
Moles, A
影响因子：
3.7
作者：
Chabout J;Serreau P;Ey E;Bellier L;Aubin T;Bourgeron T;Granon S
通讯作者：
Granon S