Bacterial elimination via the photodynamic activity of a fullerene/light-harvesting antenna molecule assembled system integrated into liposome membranes.
Bacterial elimination via the photodynamic activity of a fullerene/light-harvesting antenna molecule assembled system integrated into liposome membranes.
复制标题
通过整合到脂质体膜中的富勒烯/捕光天线分子组装系统的光动力活性消除细菌。
DOI:
10.1039/d0na00132e
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发表时间:
2020-10-13
影响因子:
4.7
通讯作者:
中科院分区:
文献类型:
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作者:
Ease of transmission and exceptionally high mortality rates make pathogen-based infections an ongoing global threat. Herein, a facile bacterial elimination process is described which is based on the photodynamic activity of fullerenes composed of light-harvesting antenna molecules integrated into liposome membranes. This was done to expand the absorption capabilities of fullerene derivatives. Efficient energy transfer from the photoactivated antenna molecules to the fullerenes enhanced antimicrobial activity without any harmful lytic activity against red blood cells even under irradiation. Bacterial elimination was attained by singlet oxygen (1O2) generated from fullerene derivatives via efficient energy transfer from photo-activated light-harvesting antenna molecules.
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DOI:
10.1038/nrd.2017.162
发表时间:
2018-01
期刊:
Nature reviews. Drug discovery
影响因子:
--
作者:
Kaufmann SHE;Dorhoi A;Hotchkiss RS;Bartenschlager R
通讯作者:
Bartenschlager R
影响因子:
15
作者:
LINDIG, BA;RODGERS, MAJ;SCHAAP, AP
通讯作者:
SCHAAP, AP
影响因子:
4.2
作者:
Ikeda, Atsushi;Akiyama, Motofusa;Takeya, Tatsuo
通讯作者:
Takeya, Tatsuo
DOI:
10.1039/c8pp00195b
发表时间:
2018-11-01
期刊:
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
影响因子:
--
作者:
Hamblin MR
通讯作者:
Hamblin MR
DOI:
10.1038/nrmicro.2018.28
发表时间:
2018-04-01
期刊:
Nature reviews. Microbiology
影响因子:
--
作者:
Du Toit, Andrea
通讯作者:
Du Toit, Andrea