T2*-based fiber orientation mapping.
T2*-based fiber orientation mapping.
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DOI：
10.1016/j.neuroimage.2011.04.026
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发表时间：
2011-07-01
期刊：
影响因子：
5.7
通讯作者：
Duyn, Jeff H.
中科院分区：
文献类型：
--
作者：
Lee, Jongho;van Gelderen, Peter;Kuo, Li-Wei;Merkle, Hellmut;Silva, Afonso C.;Duyn, Jeff H.
关键词：
Recent MRI studies at high field have observed that, in certain white matter fiber bundles, the signal in T2*-weighted MRI (i.e. MRI sensitized to apparent transverse relaxivity) is dependent on fiber orientation θ relative to B0. In this study, the characteristics of this dependency are quantitatively investigated at 7 T using ex-vivo brain specimens, which allowed a large range of rotation angles to be measured. The data confirm the previously suggested variation of R2* (= 1/T2*) with θ and also indicate that this dependency takes the shape of a combination of sin2θ and sin4θ functions, with modulation amplitudes (= ΔR2*) reaching 6.44 ± 0.15 Hz (or ΔT2* = 2.91 ± 0.33 ms) in the major fiber bundles of the corpus callosum. This particular dependency can be explained by a model of local, sub-voxel scale magnetic field changes resulting from magnetic susceptibility sources that are anisotropic. As an illustration of a potential use of the orientation dependence of R2*, the feasibility of generating fiber orientation maps from R2* data is investigated.
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影响因子：
4.2
作者：
CONNOR, JR;MENZIES, SL;MUFSON, EJ
通讯作者：
MUFSON, EJ
影响因子：
14.5
作者：
MILLER, DH;RUDGE, P;MCDONALD, WI
通讯作者：
MCDONALD, WI
DOI：
10.1073/pnas.0910222107
发表时间：
2010-03-16
影响因子：
11.1
作者：
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通讯作者：
Duyn, Jeff H.
DOI：
10.1073/pnas.0610821104
发表时间：
2007-07-10
影响因子：
11.1
作者：
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通讯作者：
Fukunaga, Masaki
影响因子：
2.5
作者：
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