The epidemiology of methicillin-resistant Staphylococcus aureus on a burn trauma unit.
The epidemiology of methicillin-resistant Staphylococcus aureus on a burn trauma unit.
复制标题
烧伤病房耐甲氧西林金黄色葡萄球菌的流行病学。
DOI：
10.1086/668032
复制
发表时间：
2012
影响因子：
4.5
通讯作者：
Herwaldt,Loreen
中科院分区：
文献类型：
--
作者：
Schweizer,Marin;Ward,Melissa;Cobb,Sandra;McDanel,Jennifer;Leder,Laurie;Wibbenmeyer,Lucy;Latenser,Barbara;Diekema,Daniel;Herwaldt,Loreen
我们评估了耐甲氧西林金黄色葡萄球菌（MRSA）分离株的频率和相关性，以确定医护人员，环境或住院患者是否可能是烧伤创伤病房（BTU）MRSA的储存库。我们还评估了BTU患者中MRSA定植的风险因素。设计前瞻性队列研究和MRSA携带监测。设置中西部学术医疗中心的BTU。患者和参与者2009年2月至2010年1月入住BTU的患者和同一时期该单位的医护人员。方法在所有BTU患者入院时从鼻孔和伤口收集MRSA培养样本。我们也从每月12位病人的咽喉、腋窝、肘前窝、腹股沟和肛周收集培养样本。从医护人员的鼻孔和环境站点收集的样本每季度进行培养。MRSA菌株进行了分型脉冲场凝胶electrophoresis.ResultsOf 144例，24（17%）进行MRSA在他们的鼻孔入院。男性性（比值比[OR]，5.51; 95%置信区间[95% CI]，1.25-24.30），因坏死性筋膜炎入院（OR，7.66; 95%CI，1.64-35.81），MRSA定植于鼻孔以外的部位（OR，23.40; 95%CI，6.93-79.01）是MRSA鼻携带的独立预测因子。从4名医护人员和4名环境培养中采集的样本培养结果呈阳性。两名患者定植菌株是无法区分的菌株收集从一个医护人员或environment.ConclusionsPatients是MRSA的主要水库。感染控制工作的重点应该是防止MRSA从MRSA携带者的患者传播给该单位的其他患者。
ObjectiveWe assessed the frequency and relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates to determine whether healthcare workers, the environment, or admitted patients could be a reservoir for MRSA on a burn trauma unit (BTU). We also assessed risk factors for MRSA colonization among BTU patients.DesignProspective cohort study and surveillance for MRSA carriage.SettingBTU of a Midwestern academic medical center.Patients and ParticipantsPatients admitted to a BTU from February 2009 through January 2010 and healthcare workers on this unit during the same time period.MethodsSamples for MRSA culture were collected on admission from the nares and wounds of all BTU patients. We also had collected culture samples from the throat, axilla, antecubital fossa, groin, and perianal area of 12 patients per month. Samples collected from healthcare workers' nares and from environmental sites were cultured quarterly. MRSA isolates were typed by pulsed-field gel electrophoresis.ResultsOf 144 patients, 24 (17%) carried MRSA in their nares on admission. Male sex (odds ratio [OR], 5.51; 95% confidence interval [95% CI], 1.25–24.30), admission for necrotizing fasciitis (OR, 7.66; 95% CI, 1.64–35.81), and MRSA colonization of a site other than the nares (OR, 23.40; 95% CI, 6.93–79.01) were independent predictors of MRSA nasal carriage. Cultures of samples collected from 4 healthcare workers and 4 environmental cultures had positive results. Two patients were colonized with strains that were indistinguishable from strains collected from a healthcare worker or the environment.ConclusionsPatients were a major reservoir for MRSA. Infection control efforts should focus on preventing transmission of MRSA from patients who are MRSA carriers to other patients on the unit.
登录
查看更多内容
关于水貂诱导不育的注释。
DOI：
10.1530/jrf.0.0050083
发表时间：
1963
期刊：
Journal of reproduction and fertility
影响因子：
--
作者：
O. Venge
通讯作者：
O. Venge
水貂的黄体功能：植入前黄体酮升高后垂体切除术的影响
影响因子：
2.2
作者：
B. Murphy;W. Humphrey;S. L. Shepstone
通讯作者：
S. L. Shepstone
与男性精子运输相关的生精小管的收缩性。
DOI：
10.3109/01485018108987539
发表时间：
1981
期刊：
Archives of andrology
影响因子：
--
作者：
L. Ellis;M. D. Groesbeck;C. Farr;R. Tesi
通讯作者：
R. Tesi
雌性水貂脑垂体远端的精细结构，Mustela vison
影响因子：
1.2
作者：
B. Weman
通讯作者：
B. Weman
雌性仓鼠大脑中雌二醇浓缩细胞的放射自显影定位。
影响因子：
4.1
作者：
M. S. Krieger;J. Morrell;D. Pfaff
通讯作者：
D. Pfaff