Distribution and identity of the earliest proliferating progeny of colony-forming cells in regenerating murine spleen and bone marrow.
Distribution and identity of the earliest proliferating progeny of colony-forming cells in regenerating murine spleen and bone marrow.
复制标题
再生小鼠脾脏和骨髓中集落形成细胞最早增殖后代的分布和身份。
DOI:
10.1002/aja.1001630203
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发表时间:
1982
期刊:
影响因子:
--
通讯作者:
Rosse,C
中科院分区:
文献类型:
--
作者:
Wolf,N;Rosse,C
A study was made of the sites of development and the types of cells found in very early hemopietic colomes in the mouse spleen. Two, 3, and 4 days after transplantation, the proliferating descendants of transplanted bone‐marrow cells were identified on radioautographs of spleen sections and on spleen and bone‐marrow smears of supralethally irradiated recipient mice which were injected with3H‐TdR at 12, 6, and 0.5 hours before sacrifice. Surprisingly the spleens of nontransplanted, irradiated mice contained proliferating medium and large lymphocytes in the white pulp which increased in numbers during the observation period. The early descendants of transplanted cells that lodged in the spleen could be clearly distinguished from the labeled indigenous cells because they formed discrete nodules or colonies beneath the splenic capsule or in the vicinity of venules and trabeculae of the red pulp. These cells were identifiable on day 2 as transitional cells or unknown hemopoietic blasts and on day 4 included early erythroid cells and small lymphocytes. There was evidence for the traffic of3H‐TdR‐labeled cells through the splenic sinusoids.
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影响因子:
8.5
作者:
N. Wolf
通讯作者:
N. Wolf
影响因子:
2.6
作者:
J. R. Zucali;G. van Zant;F. Rakowitz;A. S. Gordon
通讯作者:
A. S. Gordon
DOI:
10.3181/00379727-145-37843
发表时间:
1974
影响因子:
--
作者:
J. R. Zucali;Frederic Rakowitz;G. van Zant;A. S. Gordon
通讯作者:
A. S. Gordon
影响因子:
8.5
作者:
S. Lahiri;L. V. van Putten
通讯作者:
L. V. van Putten
DOI:
--
发表时间:
1978
期刊:
Blood cells
影响因子:
--
作者:
M. Bessis;C. Mize;M. Prenant
通讯作者:
M. Prenant