Egg Consumption and Risk of Bladder Cancer: A Meta-Analysis
Egg Consumption and Risk of Bladder Cancer: A Meta-Analysis
复制标题
鸡蛋消费与膀胱癌风险：荟萃分析
DOI：
10.1080/01635581.2013.770041
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发表时间：
2013-05
影响因子：
2.9
通讯作者：
Tan, Wan-long
中科院分区：
文献类型：
--
作者：
Du, Yue-Jun;Zhang, Xin-ji;Olkkonen, Vesa M.;Tan, Wan-long
关于鸡蛋消费与膀胱癌风险之间关系的流行病学研究结果仍然相互矛盾。我们进行了一项荟萃分析，以澄清鸡蛋消费和膀胱癌风险之间的潜在关联。截至2012年2月，PubMed数据库中发现了4项队列研究和9项病例对照研究，涉及2715例病例和184，727名参与者。随机效应模型被用来计算相对风险估计（SRRE）的基础上，最高的鸡蛋消费量与最低的类别相比。此外，我们进行了分层分析和敏感性和剂量反应分析，以检查相关性。总体而言，鸡蛋消费和膀胱癌之间没有观察到显着的关联（SRRE = 1.11 95%CI：0.90-1.35）。然而，在北美/南美检测到膀胱癌的风险增加（SRRE = 1.40，95% CI：1.05-1.86），此外，煎蛋摄入量与膀胱癌呈正相关（SRRE = 2.04，95% CI：1.41-2.95）。总之，我们的研究结果表明，鸡蛋消费和膀胱癌风险之间没有显着关联，除了基于有限数量的研究与煎蛋摄入量可能存在正相关关系。需要进一步的研究，特别是大型前瞻性队列研究来证实这些发现。
The findings of epidemiologic studies on the association between egg consumption and bladder cancer risk remain conflicting. We conducted a meta-analysis to clarify the potential association between egg consumption and bladder cancer risk. Four cohort studies and 9 case–control studies in the PubMed database through February 2012 were identified on egg consumption and risk of bladder cancer involving 2715 cases and 184,727 participants. Random-effects models were used to calculate the summary relative risk estimates (SRRE) based on the highest compared with the lowest category of egg consumption. In addition, we performed stratified analyses and sensitivity and dose-response analyses to examine the association. Overall, no significant association was observed between egg consumption and bladder cancer (SRRE = 1.11 95% CI: 0.90–1.35). However, increased risk of bladder cancer was detected in North/South America (SRRE = 1.40 95% CI: 1.05–1.86) and, moreover, fried egg intake positively associated with bladder cancer as well (SRRE = 2.04, 95% CI: 1.41–2.95). In conclusion, our findings suggest no significant association between egg consumption and bladder cancer risk, except for a possible positive relationship with the intake of fried eggs based on the limited number of studies. Additional studies, especially large prospective cohort studies, are warranted to confirm these findings.
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影响因子：
2.9
作者：
LAVECCHIA, C;NEGRI, E;FRANCESCHI, S
通讯作者：
FRANCESCHI, S
影响因子：
7
作者：
Wiseman, Martin
通讯作者：
Wiseman, Martin
影响因子：
2.1
作者：
Silberstein, Jonathan L.;Parsons, J. Kellogg
通讯作者：
Parsons, J. Kellogg
DOI：
--
发表时间：
1996-03
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
L. Wilkens;M. M. Kadir-M.;L. Kolonel;A. Nomura;J. Hankin
通讯作者：
L. Wilkens;M. M. Kadir-M.;L. Kolonel;A. Nomura;J. Hankin
DOI：
10.1207/s15327914nc381_3
发表时间：
2000-09
期刊：
Nutrition and Cancer
影响因子：
--
作者：
K. Wakai;Munehisa Takashi;K. Okamura;H. Yuba;Koh-ichi Suzuki;T. Murase;K. Obata;H. Itoh;Takanori Kato;M. Kobayashi;T. Sakata;Toshikazu Otani;Shin-ichi Ohshima;Y. Ohno
通讯作者：
K. Wakai;Munehisa Takashi;K. Okamura;H. Yuba;Koh-ichi Suzuki;T. Murase;K. Obata;H. Itoh;Takanori Kato;M. Kobayashi;T. Sakata;Toshikazu Otani;Shin-ichi Ohshima;Y. Ohno