The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.

The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.
复制标题

国际小鼠表型联盟:对小鼠表型的过去和未来观点。

DOI:
10.1007/s00335-012-9427-x
复制
发表时间:
2012-10
期刊:
影响因子:
2.5
通讯作者:
Moore, Mark W.
Moore, Mark W.
中科院分区:
生物学4区
文献类型:
--
作者:
Brown, Steve D. M.;Moore, Mark W.

文献摘要

参考文献

被引文献

相似文献

确定所有哺乳动物基因的功能仍然是生物医学科学界在21世纪世纪面临的主要挑战。国际小鼠表型分析联盟(IMPC)在未来10年的目标是对20,000个小鼠基因进行广泛的表型分析,为哺乳动物基因功能提供前所未有的见解。这篇短文探讨了大规模小鼠表型分析的驱动因素,并概述了IMPC小鼠生产和表型分析的目标和过程。
Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.
DOI: 10.1038/nature10163
发表时间: 2011-06-15
期刊: Nature
影响因子: 64.8
作者:
Skarnes WC;Rosen B;West AP;Koutsourakis M;Bushell W;Iyer V;Mujica AO;Thomas M;Harrow J;Cox T;Jackson D;Severin J;Biggs P;Fu J;Nefedov M;de Jong PJ;Stewart AF;Bradley A
通讯作者: Bradley A
DOI: 10.1371/journal.pgen.0020118
发表时间: 2006-08-25
期刊: PLoS genetics
影响因子: 4.5
作者:
Brown SD;Hancock JM;Gates H
通讯作者: Gates H
DOI: 10.1093/nar/gkm728
发表时间: 2008-01
影响因子: 14.9
作者:
Mallon AM;Blake A;Hancock JM
通讯作者: Hancock JM
DOI: 10.1152/physiolgenomics.00091.2010
发表时间: 2010-10
影响因子: 4.6
作者:
Zamyadi M;Baghdadi L;Lerch JP;Bhattacharya S;Schneider JE;Henkelman RM;Sled JG
通讯作者: Sled JG
DOI: 10.1126/science.1068206
发表时间: 2002-04-19
期刊: SCIENCE
影响因子: 56.9
作者:
Sharpe, J;Ahlgren, U;Davidson, D
通讯作者: Davidson, D