The RAST Server: rapid annotations using subsystems technology.
The RAST Server: rapid annotations using subsystems technology.
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DOI：
10.1186/1471-2164-9-75
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发表时间：
2008-02-08
期刊：
影响因子：
4.4
通讯作者：
Zagnitko O
中科院分区：
文献类型：
--
作者：
Aziz RK;Bartels D;Best AA;DeJongh M;Disz T;Edwards RA;Formsma K;Gerdes S;Glass EM;Kubal M;Meyer F;Olsen GJ;Olson R;Osterman AL;Overbeek RA;McNeil LK;Paarmann D;Paczian T;Parrello B;Pusch GD;Reich C;Stevens R;Vassieva O;Vonstein V;Wilke A;Zagnitko O
可用的原核基因组序列的数量稳定增长，并且增长的速度比我们准确注释它们的能力更快。
我们描述了用于注释细菌和古细菌基因组的全自动服务。该服务识别蛋白质编码，rRNA和TRNA基因，将功能分配给基因可容易为用户下载的输出。
该服务通常会在提交的12-24小时内提供注释的基因组，但最终将根据准确性，一致性和完整性来判断这种服务的质量。讨论逐步增强服务的计划。
通过向社区提供准确的快速注释，我们创建了一个重要的社区资源。
The number of prokaryotic genome sequences becoming available is growing steadily and is growing faster than our ability to accurately annotate them. We describe a fully automated service for annotating bacterial and archaeal genomes. The service identifies protein-encoding, rRNA and tRNA genes, assigns functions to the genes, predicts which subsystems are represented in the genome, uses this information to reconstruct the metabolic network and makes the output easily downloadable for the user. In addition, the annotated genome can be browsed in an environment that supports comparative analysis with the annotated genomes maintained in the SEED environment. The service normally makes the annotated genome available within 12–24 hours of submission, but ultimately the quality of such a service will be judged in terms of accuracy, consistency, and completeness of the produced annotations. We summarize our attempts to address these issues and discuss plans for incrementally enhancing the service. By providing accurate, rapid annotation freely to the community we have created an important community resource. The service has now been utilized by over 120 external users annotating over 350 distinct genomes.
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影响因子：
14.9
作者：
Benson DA;Karsch-Mizrachi I;Lipman DJ;Ostell J;Sayers EW
通讯作者：
Sayers EW
影响因子：
14.9
作者：
Kanehisa M;Araki M;Goto S;Hattori M;Hirakawa M;Itoh M;Katayama T;Kawashima S;Okuda S;Tokimatsu T;Yamanishi Y
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Yamanishi Y
影响因子：
14.9
作者：
Tatusov, RL;Natale, DA;Koonin, EV
通讯作者：
Koonin, EV
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3
作者：
DeJongh M;Formsma K;Boillot P;Gould J;Rycenga M;Best A
通讯作者：
Best A
影响因子：
14.9
作者：
Haft, DH;Loftus, BJ;White, O
通讯作者：
White, O