Association between Dietary Carotenoid Intake and Bone Mineral Density in Korean Adults Aged 30-75 Years Using Data from the Fourth and Fifth Korean National Health and Nutrition Examination Surveys (2008-2011).
Association between Dietary Carotenoid Intake and Bone Mineral Density in Korean Adults Aged 30-75 Years Using Data from the Fourth and Fifth Korean National Health and Nutrition Examination Surveys (2008-2011).
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DOI：
10.3390/nu9091025
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发表时间：
2017-09-16
期刊：
影响因子：
5.9
通讯作者：
Kwon O
中科院分区：
文献类型：
--
作者：
Regu GM;Kim H;Kim YJ;Paek JE;Lee G;Chang N;Kwon O
与年龄相关的骨质流失是一个主要的公共健康问题。这项横断面研究考察了饮食中类胡萝卜素的摄入量与骨密度(BMD)之间的关系。分析了韩国国民健康与营养检查调查(2008-2011年)中年龄在30-75岁的8022名受试者(男性3763名，女性4259名)的数据。采用双能X线骨密度仪测定骨密度。类胡萝卜素的摄入量是通过24小时的饮食回忆来估计的。多元线性分析显示，在男性和绝经前女性中，叶黄素+玉米黄质和β-隐黄素摄入量分别与全髋骨密度呈正相关，而在绝经后女性中，β-胡萝卜素摄入量与股骨颈、全髋骨和全身骨密度呈正相关。调整协变量后，绝经后妇女在每日β-胡萝卜素摄入量的最高五分位数中，腰椎骨质减少的风险(优势比：0.35，95%CI：0.16-0.79，趋势=0.009)低于最低五分位数的妇女。在绝经后妇女中，每天摄入β-隐黄素与全髋部(每增加1毫克/天的OR：0.76；95%可信区间：0.59-0.97)和腰椎(每增加1毫克/天的OR：0.79；95%可信区间：0.70-0.89)的骨量减少风险显著相关。这些结果表明，膳食中β-胡萝卜素和β-隐黄质的摄入可能对骨骼健康有积极的影响。
Age-related bone loss is a major public health problem. This cross-sectional study examined the association between the dietary intake of carotenoids and bone mineral density (BMD). Data from 8022 subjects (3763 males and 4259 females) aged 30–75 years included in the Korean National Health and Nutrition Examination Survey (2008–2011) were analyzed. BMD was measured by dual-energy X-ray absorptiometry. Intake of carotenoids was estimated using 24-h dietary recall. In multiple linear analysis, after adjusting for covariates, lutein + zeaxanthin and β-cryptoxanthin intake was positively associated with total hip BMD in males and premenopausal women respectively, while β-carotene intake was positively correlated with femoral neck, total hip, and whole-body BMD in postmenopausal women. Postmenopausal women in the highest quintile of daily β-carotene intake, showed a lower risk of osteopenia at the lumbar spine (odds ratio (OR): 0.35, 95% CI: 0.16–0.79, P for trend = 0.009) than those in the lowest quintile, after adjusting for covariates. Daily β-cryptoxanthin intake was significantly associated with a lower risk of osteopenia at the total hip (OR per 1 mg/day increase: 0.76; 95% CI: 0.59–0.97), and lumbar spine (OR per 1 mg/day increase: 0.79; 95% CI: 0.70–0.89) in postmenopausal women. These results suggest that the dietary intake of β-carotene and β-cryptoxanthin may have a positive effect on bone health.
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影响因子：
6.2
作者：
Dai, Zhaoli;Wang, Renwei;Ang, Li-Wei;Low, Yen-Ling;Yuan, Jian-Min;Koh, Woon-Puay
通讯作者：
Koh, Woon-Puay
影响因子：
4
作者：
Kong, S. H.;Kim, J. H.;Shin, C. S.
通讯作者：
Shin, C. S.
影响因子：
7.1
作者：
Okubo, Hitomi;Sasaki, Satoshi;Kayama, Fujio
通讯作者：
Kayama, Fujio
影响因子：
4
作者：
Sugiura, M.;Nakamura, M.;Yano, M.
通讯作者：
Yano, M.
影响因子：
5.9
作者：
Kruger MC;Wolber FM
通讯作者：
Wolber FM