Radiographic and Histomorphometric Evaluation of Biomaterials Used for Lateral Sinus Augmentation: A Systematic Review on the Effect of Residual Bone Height and Vertical Graft Size on New Bone Formation and Graft Shrinkage.
Radiographic and Histomorphometric Evaluation of Biomaterials Used for Lateral Sinus Augmentation: A Systematic Review on the Effect of Residual Bone Height and Vertical Graft Size on New Bone Formation and Graft Shrinkage.
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DOI：
10.3390/jcm10214996
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发表时间：
2021-10-27
影响因子：
3.9
通讯作者：
Del Fabbro M
中科院分区：
文献类型：
--
作者：
Pesce P;Menini M;Canullo L;Khijmatgar S;Modenese L;Gallifante G;Del Fabbro M
本系统综述的目的是研究使用不同生物材料进行侧窦提升后，残余骨高度（RBH）和垂直骨增量对新骨形成（NBF）和移植物收缩的影响。研究方法：对三个数据库进行了电子检索，以识别截至2021年1月发表的随机对照试验（RCT），其中至少有一次6个月随访，至少有5名患者接受治疗，比较了用于上颌窦提升的生物材料与外侧入路。对移植物体积变化、RBH、垂直骨增量、植入物失效和术后并发症进行了评价。使用科克伦工具评估偏倚风险。结果：我们使用了4010个识别的研究，其中21个是RCT。总体而言，对412例患者和533个鼻窦进行了评价。只有3篇出版物的偏倚风险总体较低。6个月后，异种移植物（XG）的体积减少最少（7.30 ± 15.49%），而自体移植物（Au）的重吸收最多（41.71 ± 12.63%）。NBF似乎与RBH没有直接相关性;相反，总体线性回归分析显示，术后垂直移植物每增加1 mm，NBF显著降低1.6%。这一发现表明，增加越大，NBF越低。一个类似的趋势，与回归系数甚至高于整体，也观察到与异体（AP）和XG。结论：目前的结果表明，NBF基本上是独立的术前骨高度。相反，移植物体积越小，新骨形成量越高，移植物收缩越小。最大限度地减少增强体积可能有利于移植物愈合和稳定性，尤其是在使用AP和XG时。
The aim of the present systematic review was to investigate the effect of residual bone height (RBH) and vertical bone gain on new bone formation (NBF) and graft shrinkage after lateral sinus lifts using different biomaterials. Methods: An electronic search was conducted on three databases to identify randomized controlled trials (RCTs) published until January 2021 with at least one follow-up at 6 months and at least five patients treated, comparing biomaterials used for maxillary sinus augmentation with a lateral approach. Graft volumetric changes, RBH, vertical bone gain, implant failure, and post-operative complications were evaluated. The risk of bias was assessed using the Cochrane tool. Results: We used 4010 identified studies, of which 21 were RCTs. Overall, 412 patients and 533 sinuses were evaluated. Only three publications had an overall low risk of bias. After 6 months, xenograft (XG) showed the least volume reduction (7.30 ± 15.49%), while autogenous graft (AU) was the most reabsorbed (41.71 ± 12.63%). NBF appeared to not be directly correlated with RBH; on the contrary, the overall linear regression analysis showed that NBF significantly decreased by 1.6% for each mm of postoperative vertical graft gain. This finding suggests that the greater the augmentation, the lower the NBF. A similar tendency, with a regression coefficient even higher than the overall one, was also observed with alloplast (AP) and XG. Conclusions: The present results suggested that NBF was essentially independent of preoperative bone height. On the contrary, the smaller the volume was of the graft placed, the higher the amount of new bone formed, and the smaller the graft shrinkage was. Minimizing the augmentation volume might be beneficial to graft healing and stability especially when using AP and XG.
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影响因子：
4.3
作者：
Chackartchi, Tali;Iezzi, Giovana;Shapira, Lior
通讯作者：
Shapira, Lior
影响因子：
3.4
作者：
Gerken, Ulrike;Esser, Felix;Steiner, Timm
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影响因子：
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作者：
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通讯作者：
Nissan, Joseph
DOI：
10.1002/ar.23276
发表时间：
2015-12-01
影响因子：
2
作者：
Derjac-Arama, A. I.;Sarafoleanu, C.;Rusu, M. C.
通讯作者：
Rusu, M. C.
影响因子：
4.3
作者：
Gruber, R;Kandler, B;Watzek, G
通讯作者：
Watzek, G