Biofortified Yellow-Fleshed Potatoes Provide More Absorbable Zinc than a Commonly Consumed Variety: A Randomized Trial Using Stable Isotopes in Women in the Peruvian Highlands.
Biofortified Yellow-Fleshed Potatoes Provide More Absorbable Zinc than a Commonly Consumed Variety: A Randomized Trial Using Stable Isotopes in Women in the Peruvian Highlands.
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DOI：
10.1016/j.tjnut.2023.08.028
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发表时间：
2023-10
期刊：
影响因子：
--
通讯作者：
Fairweather-Tait S
中科院分区：
文献类型：
--
作者：
Liria-Domínguez R;Penny M;Kroon PA;Burgos G;Dainty J;Zeder C;Zimmermann MB;King J;Mithen R;Boy E;Al-Jaiballi O;Fairweather-Tait S
锌生物强化马铃薯具有相当大的潜力，以减少锌缺乏症，因为他们的低水平的植酸盐，锌吸收的抑制剂，和他们的高消费量，特别是在安第斯地区的秘鲁。本研究的目的是测量分数和总锌吸收的生物强化与普通土豆相比，从测试餐。我们进行了一项单盲随机交叉研究（使用67 Zn和70 Zn稳定同位素），其中37名女性每天两次食用500 g生物强化或普通土豆。收集尿液样本，以确定分数和总锌吸收。生物强化马铃薯和普通马铃薯的锌含量分别为0.48（标准差[SD]：0.02）和0.32（SD：0.03）mg/100 g鲜重。生物强化马铃薯的锌吸收率（FZA）低于普通马铃薯，分别为20.8%（SD：5.4%）和25.5%（SD：7.0%）（P < 0.01）。但总锌吸收量显著高于对照组（分别为0.49; SD：0.13和0.40; SD：0.11 mg/500 g，P < 0.01）。这项研究的结果表明，生物强化土豆比普通土豆提供更多的可吸收锌。锌生物强化马铃薯可以有助于减少马铃薯为主食的人群中的锌缺乏症。本试验在clinicaltrials.gov上注册为NCT 05154500。
Zinc-biofortified potatoes have considerable potential to reduce zinc deficiency because of their low levels of phytate, an inhibitor of zinc absorption, and their high consumption, especially in the Andean region of Peru. The purpose of this study was to measure fractional and total zinc absorption from a test meal of biofortified compared with regular potatoes. We undertook a single-blinded randomized crossover study (using 67Zn and 70Zn stable isotopes) in which 37 women consumed 500-g biofortified or regular potatoes twice a day. Urine samples were collected to determine fractional and total zinc absorption. The zinc content of the biofortified potato and regular potato was 0.48 (standard deviation [SD]: 0.02) and 0.32 (SD: 0.03) mg/100 g fresh weight, respectively. Mean fractional zinc absorption (FZA) from the biofortified potatoes was lower than from the regular potatoes, 20.8% (SD: 5.4%) and 25.5% (SD: 7.0%), respectively (P < 0.01). However, total zinc absorbed was significantly higher (0.49; SD: 0.13 and 0.40; SD: 0.11 mg/500 g, P < 0.01, respectively). The results of this study demonstrate that biofortified potatoes provide more absorbable zinc than regular potatoes. Zinc-biofortified potatoes could contribute toward reducing zinc deficiency in populations where potatoes are a staple food. This trial was registered at clinicaltrials.gov as NCT05154500.
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DOI：
10.3390/molecules26123509
发表时间：
2021-06-09
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
Praharaj S;Skalicky M;Maitra S;Bhadra P;Shankar T;Brestic M;Hejnak V;Vachova P;Hossain A
通讯作者：
Hossain A
影响因子：
3.3
作者：
通讯作者：
--
影响因子：
4.3
作者：
Burgos, G.;Auqui, S.;Bonierbale, M.
通讯作者：
Bonierbale, M.
影响因子：
7.1
作者：
Paganini, Daniela;Uyoga, Mary A.;Zimmermann, Michael B.
通讯作者：
Zimmermann, Michael B.
DOI：
10.1093/ajcn/nqab379
发表时间：
2022-03-04
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Jongstra R;Hossain MM;Galetti V;Hall AG;Holt RR;Cercamondi CI;Rashid SF;Zimmermann MB;Mridha MK;Wegmueller R
通讯作者：
Wegmueller R