Development of an ex vivo protocol to model bone fracture in laying hens resulting from collisions.
Development of an ex vivo protocol to model bone fracture in laying hens resulting from collisions.
复制标题
DOI：
10.1371/journal.pone.0066215
复制
发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Tarlton JF
中科院分区：
文献类型：
--
作者：
Toscano MJ;Wilkins LJ;Millburn G;Thorpe K;Tarlton JF
龙骨（从胸骨向腹侧延伸的骨骼）骨折是散养蛋鸡中严重的健康和福利问题。最近的研究结果表明，在广泛的系统内龙骨损坏的一个主要原因是与内部住房结构的碰撞，虽然调查工作一直受到阻碍的困难，在审查机制和可能的影响因素在断裂的时刻。本研究的目的是开发一个离体的影响协议，以模拟碰撞引起的母鸡骨折，评估影响和鸟类相关因素影响骨折的发生和严重程度，并确定不同骨骼部位之间的机械和结构特性的相关性。我们使用能够产生一系列冲击能量的落重冲击测试仪在安乐死的母鸡中诱导龙骨骨折，产生的骨折与商业环境中常见的骨折相同。结果表明，与正常外壳中预期的冲击能量相似的冲击能量能够产生断裂，并且更大的碰撞能量导致断裂的可能性增加和更严重的程度。还发现了与龙骨侧面骨密度和胸骨柄棘底部峰值反作用力（强度）的关系。龙骨和长骨之间的相关性也被确定为强度和骨矿物质密度。这是第一项能够将碰撞和骨骼特征与碰撞时龙骨骨折联系起来的研究。更好地理解这些关系将提供降低商业系统中破损程度和严重程度的方法。
Fractures of the keel bone, a bone extending ventrally from the sternum, are a serious health and welfare problem in free range laying hens. Recent findings suggest that a major cause of keel damage within extensive systems is collisions with internal housing structures, though investigative efforts have been hindered by difficulties in examining mechanisms and likely influencing factors at the moment of fracture. The objectives of this study were to develop an ex vivo impact protocol to model bone fracture in hens caused by collision, to assess impact and bird-related factors influencing fracture occurrence and severity, and to identify correlations of mechanical and structural properties between different skeletal sites. We induced keel bone fractures in euthanized hens using a drop-weight impact tester able to generate a range of impact energies, producing fractures that replicate those commonly found in commercial settings. The results demonstrated that impact energies of a similar order to those expected in normal housing were able to produce fractures, and that greater collision energies resulted in an increased likelihood of fractures and of greater severity. Relationships were also seen with keel’s lateral surface bone mineral density, and the peak reactive force (strength) at the base of the manubrial spine. Correlations were also identified between the keel and long bones with respect to both strength and bone mineral density. This is the first study able to relate impact and bone characteristics with keel bone fracture at the moment of collision. Greater understanding of these relationships will provide means to reduce levels of breakage and severity in commercial systems.
登录
查看更多内容
影响因子：
2
作者：
HEWSON, P
通讯作者：
HEWSON, P
影响因子：
2.4
作者：
Dunn, I. C.;Fleming, R. H.;Whitehead, C. C.
通讯作者：
Whitehead, C. C.
影响因子：
2
作者：
Bishop, SC;Fleming, RH;Whitehead, CC
通讯作者：
Whitehead, CC
影响因子：
4.4
作者：
Donaldson, C. J.;Ball, M. E. E.;O'Connell, N. E.
通讯作者：
O'Connell, N. E.
影响因子：
4.1
作者：
Tarlton, John F.;Wilkins, Lindsay J.;Knott, Lynda
通讯作者：
Knott, Lynda