Smoking Is Associated with Higher Intraocular Pressure Regardless of Glaucoma: A Retrospective Study of 12.5 Million Patients Using the Intelligent Research in Sight (IRIS®) Registry.
Smoking Is Associated with Higher Intraocular Pressure Regardless of Glaucoma: A Retrospective Study of 12.5 Million Patients Using the Intelligent Research in Sight (IRIS®) Registry.
复制标题
吸烟与较高的眼内压有关，无论青光眼如何：使用智能研究（IRIS®）注册中心对1,250万患者的回顾性研究。
DOI：
10.1016/j.ogla.2020.03.008
复制
发表时间：
2020-07
影响因子：
--
通讯作者：
Lee AY
中科院分区：
文献类型：
--
作者：
Lee CS;Owen JP;Yanagihara RT;Lorch A;Pershing S;Hyman L;Miller JW;Haller JA;Chiang MF;Lum F;Lee AY
使用美国眼科学会视力智能研究 (IRIS) 注册中心比较吸烟者、过去吸烟者和从不吸烟者的平均眼压 (IOP)。 IRIS 注册数据的回顾性数据库研究。对 2017 年眼科护理人员就诊的视力登记患者进行智能研究。患者被分为当前吸烟者、过去吸烟者和从不吸烟者三类。眼压基于平均测量值，并根据国际疾病分类第九版和第十版代码对有和没有青光眼诊断的患者进行单独分析。确定了青光眼状态的分层描述性统计数据，并使用多元线性回归模型评估了吸烟与眼压之间的关系。平均眼压。总共纳入了 12 535 013 名患者。与从不吸烟者相比，在调整年龄、性别、青光眼、年龄相关性黄斑变性、糖尿病视网膜病变、白内障、青光眼后，当前吸烟者和既往吸烟者的眼压分别显着升高 0.92 mmHg（95% 置信区间 [CI]，0.88–0.95 mmHg）和 0.77 mmHg（95% CI，0.75–0.79 mmHg）。手术、白内障手术和一阶相互作用。此外，无论青光眼状况如何，当前吸烟者和从不吸烟者之间的眼压差异在四十岁左右最高（青光眼组，1.14 mmHg [95% CI，1.00–1.29 mmHg]；无青光眼组，0.68 mmHg [95% CI，0.65–0.71 mmHg]）。当前吸烟者和过去吸烟者的眼压高于从不吸烟的患者。这种差异在患有潜在青光眼诊断的患者中更高。
To compare the average intraocular pressure (IOP) among smokers, past smokers, and never smokers using the American Academy of Ophthalmology Intelligent Research in Sight (IRIS) Registry. Retrospective database study of the IRIS Registry data. Intelligent Research in Sight Registry patients who were seen by an eye care provider during 2017. Patients were divided into current smoker, past smoker, and never smoker categories. The IOP was based on an average measurement, and separate analyses were performed in patients with and without a glaucoma diagnosis based on International Classification of Diseases, Ninth Edition and Tenth Edition, codes. Stratified, descriptive statistics by glaucoma status were determined, and the relationship between smoking and IOP was assessed with a multivariate linear regression model. Mean IOP. A total of 12 535 013 patients were included. Compared with never smokers, current and past smokers showed a statistically significantly higher IOP by 0.92 mmHg (95% confidence interval [CI], 0.88–0.95 mmHg) and 0.77 mmHg (95% CI, 0.75–0.79 mmHg), respectively, after adjusting for age, gender, glaucoma, age-related macular degeneration, diabetic retinopathy, cataract, glaucoma surgery, cataract surgery, and first-order interactions. In addition, the difference in IOP between current and never smokers was the highest in the fourth decade, regardless of the glaucoma status (glaucoma group, 1.14 mmHg [95% CI, 1.00–1.29 mmHg]; without glaucoma group, 0.68 mmHg [95% CI, 0.65–0.71 mmHg]). Current smokers and past smokers have higher IOP than patients who never smoked. This difference is higher in patients with an underlying glaucoma diagnosis.
登录
查看更多内容
影响因子：
13.7
作者：
Parke, D. Wilkin, III;Lum, Flora
通讯作者：
Lum, Flora
影响因子：
2
作者：
Badr, Mai;Solano, Marisse Masis;Lin, Shan
通讯作者：
Lin, Shan
影响因子：
13.7
作者：
Chiang, Michael F.;Sommer, Alfred;Parke, David W., II
通讯作者：
Parke, David W., II
影响因子：
5.2
作者：
Bonovas, S;Filioussi, K;Peponis, V
通讯作者：
Peponis, V
影响因子：
--
作者：
Kang, JH;Pasquale, LR;Hankinson, SE
通讯作者：
Hankinson, SE