Effect of energy intake on nutritional status in maintenance hemodialysis patients.

Effect of energy intake on nutritional status in maintenance hemodialysis patients.
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能量摄入对维持性血液透析患者营养状况的影响。

DOI:
10.1038/ki.1989.42
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发表时间:
1989
影响因子:
19.6
通讯作者:
Kopple,JD
Kopple,JD
中科院分区:
医学1区
文献类型:
--
作者:
Slomowitz,LA;Monteon,FJ;Grosvenor,M;Laidlaw,SA;Kopple,JD

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能量摄入对维持性血液透析患者营养状况的影响。尽管维持性血液透析(MHD)患者经常被浪费,但人们对他们的饮食能量需求知之甚少。我们在一个临床研究中心对四名男性和两名女性进行了研究,他们分别接受了45、35和25千卡/公斤理想体重/天的饮食;随机饲喂21 ~ 23 d。蛋白质摄取量为1.13±0.02 (SEM) g蛋白质/kg/d,与3种日粮相似。体重以45和35 kcal/kg/d上升(P < 0.05),以25 kcal/kg/d下降(P < 0.05)。根据估计的未测量损失进行调整后,氮平衡为中性,为45和35千卡/公斤/天,为负,为25千卡/公斤/天。分别饲喂45、35、25千卡/公斤/天的6例患者中有6例、6例中有4例和6例中0例平衡为中性或阳性。氮平衡、许多血浆氨基酸以及体重、臂中围、臂中肌肉面积和体脂的变化均与能量摄入相关。静息能量消耗正常。由回归方程估计维持中性氮平衡的能量摄入为38.5千卡/公斤理想体重/天;对于体脂和体重,为32千卡/公斤/天。这些数据表明MHD患者有正常的能量消耗和维持蛋白质平衡、体重和体脂的基本正常需求。在这些患者中,维持氮平衡可能需要约38千卡/公斤理想体重/天的平均能量摄入。
Effect of energy intake on nutritional status in maintenance hemodialysis patients. Although maintenance hemodialysis (MHD) patients are often wasted, little is known about their dietary energy needs. We studied four men and two women in a clinical research center while they received diets providing 45, 35 and 25 kcal/kg desirable body weight/day; diets were fed, in random order, for 21 to 23 days each. Protein intake, 1.13 ± 0.02 (SEM) g protein/kg/day, was similar with all three diets. Body weight rose with 45 and 35 kcal/kg/day (P < 0.05) and fell with 25 kcal/kg/day (P < 0.05). Nitrogen balance, adjusted for estimated unmeasured losses, was neutral with 45 and 35 kcal/kg/day and negative with 25 kcal/kg/day. Balance was neutral or positive in 6 of 6, 4 of 6, and 0 of 6 patients fed 45, 35, 25 kcal/kg/day, respectively. Nitrogen balance, many plasma amino acids and changes in body weight, mid-arm circumference, mid-arm muscle area and body fat each correlated with energy intake. Resting energy expenditure was normal. The energy intake estimated from regression equations to maintain neutral nitrogen balance was 38.5 kcal/kg desirable weight/day; for body fat and weight, it was 32 kcal/kg/day. These data suggest that MHD patients have normal energy expenditure and approximately normal requirements for maintenance of protein balance, body weight and body fat. An average energy intake of about 38 kcal/kg desirable weight/day may be necessary to maintain nitrogen balance in these patients.
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影响因子: 7.1
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发表时间: 1978
影响因子: 19.6
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发表时间: 1973
期刊: Medicine
影响因子: 1.6
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发表时间: 1980
影响因子: 7.1
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