Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy.

Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy.
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DOI:
10.1016/j.pbiomolbio.2014.07.011
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发表时间:
2014-08
影响因子:
3.8
通讯作者:
Efimov IR
Efimov IR
中科院分区:
生物学3区
文献类型:
--
作者:
Gutbrod SR;Sulkin MS;Rogers JA;Efimov IR

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Advances in material science techniques and pioneering circuit designs have led to the development of electronic membranes that can form intimate contacts with biological tissues. In this review, we present the range of geometries, sensors, and actuators available for custom configurations of electronic membranes in cardiac applications. Additionally, we highlight the desirable mechanics achieved by such devices that allow the circuits and substrates to deform with the beating heart. These devices unlock opportunities to collect continuous data on the electrical, metabolic, and mechanical state of the heart as well as a platform on which to develop high definition therapeutics.
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