Effect of smoking on subgingival microflora of patients with periodontitis in Japan.
Effect of smoking on subgingival microflora of patients with periodontitis in Japan.
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DOI：
10.1186/1472-6831-11-1
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发表时间：
2011-01-05
期刊：
影响因子：
2.9
通讯作者：
Ishihara K
中科院分区：
文献类型：
--
作者：
Kubota M;Tanno-Nakanishi M;Yamada S;Okuda K;Ishihara K
吸烟是牙周炎的一个危险因素。为了阐明吸烟对牙周炎的影响，有必要评估吸烟与龈下菌群之间的关系。本研究的目的是深入了解吸烟对日本牙周炎患者微生物区系的影响。67例日本慢性牙周炎患者（19 - 83岁，女性23例，男性44例）参加了本研究。他们包括30名吸烟者和37名不吸烟者。记录牙周检查参数，包括探诊袋深度（PPD）和探诊出血（BOP）以及口腔卫生状况。聚合酶链反应检测龈下菌斑标本中伴放线菌聚集菌、牙龈卟啉单胞菌、中间普雷沃菌、嗜酸坦纳菌、具核/牙周梭杆菌、齿垢密螺旋体和直弯杆菌。采用多元Logistic回归分析和卡方检验分析牙周致病菌检出率与吸烟状况的关系。PPD ≥ 4 mm与T细胞检出之间存在统计学显著相关性。denticola、中间疫霉（P. intermedia）、T.或C.直肌，优势比范围为2.17至3.54。BOP和C.腹直肌或中间肌与吸烟的比值比范围为1.99至5.62。C.流行吸烟者的腹直肌高于非吸烟者，而A.吸烟者伴放线菌数较低。在一定范围内，对吸烟者和非吸烟者慢性牙周炎龈下微生物植物群的分析表明，吸烟与特定牙周病原体（包括C.直肌
Smoking is a risk factor for periodontitis. To clarify the contribution of smoking to periodontitis, it is essential to assess the relationship between smoking and the subgingival microflora. The aim of this study was to gain an insight into the influence of smoking on the microflora of Japanese patients with periodontitis. Sixty-seven Japanese patients with chronic periodontitis (19 to 83 years old, 23 women and 44 men) were enrolled in the present study. They consisted of 30 smokers and 37 non-smokers. Periodontal parameters including probing pocket depth (PPD) and bleeding on probing (BOP) and oral hygiene status were recorded. Detection of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia, Fusobacterium nucleatum/periodonticum, Treponema denticola and Campylobacter rectus in subgingival plaque samples was performed by polymerase chain reaction. Association between the detection of periodontopathic bacteria and smoking status was analyzed by multiple logistic regression analysis and chi-square test. A statistically significant association was found between having a PPD ≥ 4 mm and detection of T. denticola, P. intermedia, T. forsythia, or C. rectus, with odds ratios ranging from 2.17 to 3.54. A significant association was noted between BOP and the detection of C. rectus or P. intermedia, and smoking, with odds ratios ranging from 1.99 to 5.62. Prevalence of C. rectus was higher in smokers than non-smokers, whereas that of A. actinomycetemcomitans was lower in smokers. Within limits, the analysis of the subgingival microbial flora in smokers and non-smokers with chronic periodontitis suggests a relevant association between smoking and colonization by the specific periodontal pathogens including C. rectus.
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影响因子：
4.3
作者：
GOULTSCHIN, J;COHEN, HDS;SOSKOLNE, WA
通讯作者：
SOSKOLNE, WA
影响因子：
3.5
作者：
Ihara, H;Miura, T;Okuda, K
通讯作者：
Okuda, K
影响因子：
6.7
作者：
Darby, IB;Hedge, PJ;Kinane, DF
通讯作者：
Kinane, DF
影响因子：
4.3
作者：
GENCO, RJ
通讯作者：
GENCO, RJ
影响因子：
3.5
作者：
HAFFAJEE, AD;SOCRANSKY, SS;DIBART, S
通讯作者：
DIBART, S